caa a22 4500 465735711 CHVBK 20180323111754.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF00177841 doi (NATIONALLICENCE)springer-10.1007/BF00177841 Glioblastoma multiforme with bone metastase and cauda equina syndrome [Elektronische Daten] [Yair Lampl, Yechiel Eshel, Ronit Gilad, Ida Sarova-Pinchas] Summary: Remote metastases, leptomeningeal dissemination and spreading of the tumor by infiltration are rare complications of glioblastoma multiforme. The existence of different forms of spreading simultaneously is very rare. We present a case of a young patient with glioblastoma multiforme who was operated and subsequently received radiation therapy and cytotoxic treatment. Eight months following the operation, the patient developed cauda equina syndrome. Bone metastases of vertebrae and ribs, and direct infiltration of the recurrent tumor mass into the ethmoidal and frontal sinuses were found. The described patient demonstrates a very rare combination of all forms of spreading metastases in glioblastoma multiforme. The infiltration of the tumor mass into the sinuses and the direct permeation of the meningeal and dural venous system and of the leptomeninges, may explain the mechanism of the development of distant metastases and leptomeningeal dissemination in glioblastoma multiforme. Kluwer Academic Publishers, 1990 glioblastoma multiforme nationallicence bone metastases nationallicence seeding metastases nationallicence cauda equina syndrome nationallicence Lampl Yair Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut Eshel Yechiel Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut Gilad Ronit Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut Sarova-Pinchas Ida Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut Journal of Neuro-Oncology Kluwer Academic Publishers 8/2(1990-04-01), 167-172 0167-594X 8:2<167 1990 8 11060 https://doi.org/10.1007/BF00177841 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00177841 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Lampl Yair Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut NATIONALLICENCE 700 1- Eshel Yechiel Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut NATIONALLICENCE 700 1- Gilad Ronit Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut NATIONALLICENCE 700 1- Sarova-Pinchas Ida Department of Neurology, Edith Wolfson Medical Center, Holon and the Tel Aviv University Sackler School of Medicine, Israel aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 8/2(1990-04-01), 167-172 0167-594X 8:2<167 1990 8 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer