caa a22 4500 465735770 CHVBK 20180323111754.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF00177840 doi (NATIONALLICENCE)springer-10.1007/BF00177840 VP-16, vincristine and procarbazine with radiation therapy for treatment of malignant brain tumors [Elektronische Daten] [Richard Hellman, John Calogero, Bruce Kaplan] Summary: Twelve patients aged 34 to 65 with malignant gliomas were treated with VP-16, Procarbazine, Vincristine and concurrent radiation therapy. There were 9 patients with glioblastoma multiforme and 3 with anaplastic astrocytoma. All patients had a subtotal resection or biopsy as the initial procedure. Six patients (1 anaplastic astrocytoma) have developed progressive disease. Mean time to tumor progression was 46 weeks. This combined modality treatment program was associated with reversible hematologic toxicity which was severe in 2 patients. These data compare favorably to data obtained from similiar patients treated with radiation therapy and BCNU. Kluwer Academic Publishers, 1990 brain tumor nationallicence radiation therapy nationallicence VP-16 nationallicence procarbazine nationallicence vincristine nationallicence Hellman Richard Department of Medicine, Department of Neurosurgery and Radiation Oncology, St. Francis Hospital and Medical Center, Hartford, Connecticut aut Calogero John Department of Medicine, Department of Neurosurgery and Radiation Oncology, St. Francis Hospital and Medical Center, Hartford, Connecticut aut Kaplan Bruce Department of Medicine, Department of Neurosurgery and Radiation Oncology, St. Francis Hospital and Medical Center, Hartford, Connecticut aut Journal of Neuro-Oncology Kluwer Academic Publishers 8/2(1990-04-01), 163-166 0167-594X 8:2<163 1990 8 11060 https://doi.org/10.1007/BF00177840 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00177840 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hellman Richard Department of Medicine, Department of Neurosurgery and Radiation Oncology, St. Francis Hospital and Medical Center, Hartford, Connecticut aut NATIONALLICENCE 700 1- Calogero John Department of Medicine, Department of Neurosurgery and Radiation Oncology, St. Francis Hospital and Medical Center, Hartford, Connecticut aut NATIONALLICENCE 700 1- Kaplan Bruce Department of Medicine, Department of Neurosurgery and Radiation Oncology, St. Francis Hospital and Medical Center, Hartford, Connecticut aut NATIONALLICENCE 773 0- Journal of Neuro-Oncology Kluwer Academic Publishers 8/2(1990-04-01), 163-166 0167-594X 8:2<163 1990 8 11060 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer