caa a22 4500 465736211 CHVBK 20180323111755.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF02575467 doi (NATIONALLICENCE)springer-10.1007/BF02575467 Hepatic artery infusion and chemoembolization in the management of liver metastases [Elektronische Daten] [Sidney Wallace, C. Carrasco, Chusilp Charnsangavej, William Richli, Kenneth Wright, Cesare Gianturco] Hepatic metastases rather than the primary neoplasm usually dictate the course of the disease and the patient's survival. For unresectable disease, intraarterial infusion of chemotherapy, embolization, and chemoembolization are viable alternatives. Intraarterial therapy for hepatic metastases is based on the dual blood supply of the normal liver (portal vein, 75%, and hepatic artery, 25%) and that of the tumors (hepatic artery, 90%). Intraarterial infusion delivers a higher concentration of chemotherapy, whereas chemoembolization adds ischemia and increased contact time with the tumor. Selective vascular occlusion for infusion, redistribution of the blood supply and pulsatile flow enhance the delivery of therapeutic agents to the liver. Springer-Verlag New York Inc., 1990 Infusion nationallicence Chemoembolization nationallicence Intraarterial therapy nationallicence Hepatic metastases nationallicence Wallace Sidney The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut Carrasco C. The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut Charnsangavej Chusilp The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut Richli William The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut Wright Kenneth The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut Gianturco Cesare The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut CardioVascular and Interventional Radiology Springer-Verlag 13/3(1990-05-01), 153-160 0174-1551 13:3<153 1990 13 270 https://doi.org/10.1007/BF02575467 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02575467 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Wallace Sidney The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut NATIONALLICENCE 700 1- Carrasco C. The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut NATIONALLICENCE 700 1- Charnsangavej Chusilp The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut NATIONALLICENCE 700 1- Richli William The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut NATIONALLICENCE 700 1- Wright Kenneth The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut NATIONALLICENCE 700 1- Gianturco Cesare The Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd., 77030, Houston, Texas, USA aut NATIONALLICENCE 773 0- CardioVascular and Interventional Radiology Springer-Verlag 13/3(1990-05-01), 153-160 0174-1551 13:3<153 1990 13 270 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer