caa a22 4500 465737137 CHVBK 20180323111758.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF02244117 doi (NATIONALLICENCE)springer-10.1007/BF02244117 [ d -Pen2, d -Pen5]enkephalin, the standard delta opioid agonist, induces morphine-like behaviors in mice [Elektronische Daten] [Christopher Murray, Alan Cowan] [d-Pen2,d-Pen5]enkephalin (DPDPE; 3-30 µg) and morphine (10 µg) both caused Straub tails, increased locomotion, and circling after ICV administration to ICR mice. DPDPE-induced tail stiffening was reduced when mice were pretreated with naloxone (0.5 mg/kg SC) orβ-funaltrexamine (10 µg ICV), but not with ICI 174864 (2 mg/kg SC), the selective antagonist at delta opioid receptors. These results point to (a) mu receptors mediating the tail stiffening and (b) the loss of delta receptor selectivity after 10 and 30 µg DPDPE. Springer-Verlag, 1990 DPDPE nationallicence Straub tail nationallicence Opioid receptor selectivity nationallicence Murray Christopher Department of Pharmacology, Temple University School of Medicine, 19140, Philadelphia, PA, USA aut Cowan Alan Department of Pharmacology, Temple University School of Medicine, 19140, Philadelphia, PA, USA aut Psychopharmacology Springer-Verlag 102/3(1990-11-01), 425-426 0033-3158 102:3<425 1990 102 213 https://doi.org/10.1007/BF02244117 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02244117 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Murray Christopher Department of Pharmacology, Temple University School of Medicine, 19140, Philadelphia, PA, USA aut NATIONALLICENCE 700 1- Cowan Alan Department of Pharmacology, Temple University School of Medicine, 19140, Philadelphia, PA, USA aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 102/3(1990-11-01), 425-426 0033-3158 102:3<425 1990 102 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer