caa a22 4500 465737617 CHVBK 20180323111759.0 cr unu---uuuuu 170327e19901001xx s 000 0 eng 10.1007/BF02245926 doi (NATIONALLICENCE)springer-10.1007/BF02245926 Action of tianeptine on focalization of attention in cat [Elektronische Daten] [Philippe Delagrange, Jean-Jacques Bouyer, Marie-Françoise Montaron, Claudette Durand, Elizabeth Mocaër, Arlette Rougeul] Tianeptine, an antidepressant substance devoid of sedative action, was investigated for its effects on focalization of attention in cats, using combined behavioural and electrocorticographic (ECoG) observations. The ECoG index was the presence of 40 Hz frontoparietal rhythmic cortical activities, developing while the animal displayed a behaviour suggesting focused attention. Cats were observed in two conditions: a "neutral” one, with no specific target, and another one, "of focused attention” where a live mouse placed in a transparent box was present in the recording room, each test lasting for 90 min. After treatment the animals displayed increased attention even in the neutral situation, where the cat, instead of sleeping like during control sessions, payed sustained attention to its environment. Conversely, at corresponding doses, amitriptyline, another antidepressant drug chosen as a reference, induced uninterrupted slow sleep even in the situation of focused attention. Springer-Verlag, 1990 Tianeptine nationallicence Amitriptyline nationallicence Attention nationallicence Beta rhythms nationallicence Frontoparietal cortex nationallicence Quantitative ECoG nationallicence Cat nationallicence Delagrange Philippe Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut Bouyer Jean-Jacques Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut Montaron Marie-Françoise Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut Durand Claudette Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut Mocaër Elizabeth Institut de Recherches Internationales Servier, 6 place des Pléiades, F-92415, Courbevoie Cedex, France aut Rougeul Arlette Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut Psychopharmacology Springer-Verlag 102/2(1990-10-01), 227-233 0033-3158 102:2<227 1990 102 213 https://doi.org/10.1007/BF02245926 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245926 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Delagrange Philippe Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut NATIONALLICENCE 700 1- Bouyer Jean-Jacques Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut NATIONALLICENCE 700 1- Montaron Marie-Françoise Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut NATIONALLICENCE 700 1- Durand Claudette Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut NATIONALLICENCE 700 1- Mocaër Elizabeth Institut de Recherches Internationales Servier, 6 place des Pléiades, F-92415, Courbevoie Cedex, France aut NATIONALLICENCE 700 1- Rougeul Arlette Département de Neurophysiologie comparée, Institut des Neurosciences, CNRS Université P. & M. Curie, 9 quai St Bernard, F-75005, Paris, France aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 102/2(1990-10-01), 227-233 0033-3158 102:2<227 1990 102 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer