caa a22 4500 465738370 CHVBK 20180323111801.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF02244139 doi (NATIONALLICENCE)springer-10.1007/BF02244139 Effect of caffeine on physiological sleep tendency and ability to sustain wakefulness at night [Elektronische Daten] [James Walsh, Mark Muehlbach, Tina Humm, Q. Stokes Dickins, Jeffrey Sugerman, Paula Schweitzer] Marked sleepiness occurs during typical night shift work hours and this reduced alertness is associated with marked performance deficits. The effect of caffeine (versus placebo) upon sleepiness at night was studied using objective measures of physiological sleep tendency and ability to sustain wakefulness. Both measures show caffeine to reduce sleepiness at a single dose roughly the equivalent of two to four cups of coffee. Despite impressive objective differences in alertness with caffeine, subjects did not consistently differentiate between drug conditions on subjective alertness assessments. The use of CNS stimulants to promote alertness during night shift hours should be considered, particularly for occupations for which alertness is critical. Springer-Verlag, 1990 Sleepiness/alertness nationallicence Caffeine nationallicence Night shift nationallicence Circadian nationallicence Walsh James Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut Muehlbach Mark Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut Humm Tina Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut Stokes Dickins Q. Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut Sugerman Jeffrey Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut Schweitzer Paula Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut Psychopharmacology Springer-Verlag 101/2(1990-06-01), 271-273 0033-3158 101:2<271 1990 101 213 https://doi.org/10.1007/BF02244139 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02244139 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Walsh James Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Muehlbach Mark Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Humm Tina Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Stokes Dickins Q. Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Sugerman Jeffrey Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut NATIONALLICENCE 700 1- Schweitzer Paula Sleep Disorders and Research Center, Deaconess Hospital, 6150 Oakland Avenue, 63139, St. Louis, MO, USA aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 101/2(1990-06-01), 271-273 0033-3158 101:2<271 1990 101 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer