caa a22 4500 465738621 CHVBK 20180323111802.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02245784 doi (NATIONALLICENCE)springer-10.1007/BF02245784 State dependent and/or direct memory retrieval by morphine in mice [Elektronische Daten] [Mika Nishimura, Yasuyuki Shiigi, Hiroshi Kaneto] Mice were trained in step-down and step-through type passive avoidance learning tasks and given retention tests. Pre-training administration of morphine impaired retention, the effect recovering completely after an additional injection of the same dose of morphine given 30 min before the retention test. Amnesia produced by scopolamine, cycloheximide and electroconvulsive shock was also reversed by pre-test morphine. Pre-test saline also reversed the morphine-induced memory impairment to some extent, indicating that the recovery may partially be due to the state dependent effect. Thus, it is demonstrated that pre-test morphine not only state dependently but also directly reversed memory impairment in mice. Springer-Verlag, 1990 Morphine nationallicence Passive avoidance nationallicence Memory retrieval nationallicence Scopolamine nationallicence Cycloheximide nationallicence ECS nationallicence Naloxone nationallicence Mouse nationallicence Nishimura Mika Department of Pharmacology, Faculty of Pharmaceutical Sciences, Nagasaki University, 852, Nagasaki, Japan aut Shiigi Yasuyuki Department of Pharmacology, Faculty of Pharmaceutical Sciences, Nagasaki University, 852, Nagasaki, Japan aut Kaneto Hiroshi Department of Pharmacology, Faculty of Pharmaceutical Sciences, Nagasaki University, 852, Nagasaki, Japan aut Psychopharmacology Springer-Verlag 100/1(1990-03-01), 27-30 0033-3158 100:1<27 1990 100 213 https://doi.org/10.1007/BF02245784 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245784 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nishimura Mika Department of Pharmacology, Faculty of Pharmaceutical Sciences, Nagasaki University, 852, Nagasaki, Japan aut NATIONALLICENCE 700 1- Shiigi Yasuyuki Department of Pharmacology, Faculty of Pharmaceutical Sciences, Nagasaki University, 852, Nagasaki, Japan aut NATIONALLICENCE 700 1- Kaneto Hiroshi Department of Pharmacology, Faculty of Pharmaceutical Sciences, Nagasaki University, 852, Nagasaki, Japan aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 100/1(1990-03-01), 27-30 0033-3158 100:1<27 1990 100 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer