caa a22 4500 465738656 CHVBK 20180323111802.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02245805 doi (NATIONALLICENCE)springer-10.1007/BF02245805 Electroconvulsive treatment attenuates behavioral response to SKF 38393 in reserpine-treated mice [Elektronische Daten] [X. Hao, A. Mathé, J. Mathé, T. Svensson] Electroconvulsive treatment (ECT) of mice, once daily for 7 days, significantly reduced the stimulation of motor activity induced by the selective dopamine (DA) D1-receptor agonist SKF 38393 (15 mg/kg IP), but significantly increased the motor stimulation by the unselective DA-receptor agonist apomorphine (1.5 mg/kg IP) in reserpinetreated (10 mg/kg IP) mice, when compared to control mice, receiving sham ECT. The results provide a functional correlate to previously observed ECT-induced down-regulation of D1 receptor sites in DA-rich regions of the rodent brain. Such an effect may be significant for clinical actions of ECT in affective disorders and, possibly, in Parkinson's disease. Springer-Verlag, 1990 Electroconvulsive treatment nationallicence D1-receptor subsensitivity nationallicence Behavior nationallicence Hao X. Department of Pharmacology, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut Mathé A. Department of Psychiatry, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut Mathé J. Department of Pharmacology, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut Svensson T. Department of Pharmacology, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut Psychopharmacology Springer-Verlag 100/1(1990-03-01), 135-137 0033-3158 100:1<135 1990 100 213 https://doi.org/10.1007/BF02245805 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245805 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hao X. Department of Pharmacology, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut NATIONALLICENCE 700 1- Mathé A. Department of Psychiatry, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut NATIONALLICENCE 700 1- Mathé J. Department of Pharmacology, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut NATIONALLICENCE 700 1- Svensson T. Department of Pharmacology, Karolinska Institute and St. Göran's Hospital, Stockholm, Sweden aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 100/1(1990-03-01), 135-137 0033-3158 100:1<135 1990 100 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer