caa a22 4500 465738729 CHVBK 20180323111802.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02245794 doi (NATIONALLICENCE)springer-10.1007/BF02245794 The relationship between chronic ethanol exposure and cigarette smoking in the laboratory and the natural environment [Elektronische Daten] [Robert Keenan, Dorothy Hatsukami, Roy Pickens, Steven Gust, Loran Strelow] Few studies have examined the association between ethanol use and cigarette smoking topography. In particular, no study has objectively investigated the relationship between chronic ethanol exposure and cigarette smoking. The aim of this study was to quantify the relationship between cigarette smoking and past and current ethanol use. Male and female cigarette smokers (n=77) between the ages of 30 and 65 years were recruited and grouped as a function of their past and current ethanol use. Group 1 (n=18) included subjects who were ethanol abstinent for the 3 months prior to the study and had no history of alcohol abuse (as defined by DSM-III criteria). Group 2 (n=19) included subjects who were current regular ethanol users and had no history of alcohol abuse. Group 3 (n=20) included subjects who were ethanol abstinent and had a history of alcohol abuse. Group 4 (n=20) included current regular ethanol users with a history of alcohol abuse. A history of alcohol abuse was associated with an intensified pattern of cigarette smoking. Significant differences were observed for total daily smoke exposure, cigarette number, puff number, total puff and inhalation volume, and the nicotine, tar and carbon monoxide yields of the cigarettes smoked. Increased expired-air carbon monoxide and serum cotinine levels were also observed. Current ethanol use was not associated with an increased cigarette smoking pattern. These data suggest that alcohol abusers are at greater risk of contracting cigarette-related pathology. Springer-Verlag, 1990 Ethanol use nationallicence Cigarette smoking nationallicence Keenan Robert Tobacco Research Laboratory, Department of Psychiatry, University of Minesota Medical School, Mayo Memorial Building, 420 Delaware Street SE, Box 392, 55455, Minneapolis, MN, USA aut Hatsukami Dorothy Tobacco Research Laboratory, Department of Psychiatry, University of Minesota Medical School, Mayo Memorial Building, 420 Delaware Street SE, Box 392, 55455, Minneapolis, MN, USA aut Pickens Roy The National Institute on Drug Abuse, Room 10-A-38, Parklawn Building, 5600 Fishers Lane, 20857, Rockville, MD, USA aut Gust Steven The National Institute on Drug Abuse, Room 10-A-38, Parklawn Building, 5600 Fishers Lane, 20857, Rockville, MD, USA aut Strelow Loran Tobacco Research Laboratory, Department of Psychiatry, University of Minesota Medical School, Mayo Memorial Building, 420 Delaware Street SE, Box 392, 55455, Minneapolis, MN, USA aut Psychopharmacology Springer-Verlag 100/1(1990-03-01), 77-83 0033-3158 100:1<77 1990 100 213 https://doi.org/10.1007/BF02245794 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245794 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Keenan Robert Tobacco Research Laboratory, Department of Psychiatry, University of Minesota Medical School, Mayo Memorial Building, 420 Delaware Street SE, Box 392, 55455, Minneapolis, MN, USA aut NATIONALLICENCE 700 1- Hatsukami Dorothy Tobacco Research Laboratory, Department of Psychiatry, University of Minesota Medical School, Mayo Memorial Building, 420 Delaware Street SE, Box 392, 55455, Minneapolis, MN, USA aut NATIONALLICENCE 700 1- Pickens Roy The National Institute on Drug Abuse, Room 10-A-38, Parklawn Building, 5600 Fishers Lane, 20857, Rockville, MD, USA aut NATIONALLICENCE 700 1- Gust Steven The National Institute on Drug Abuse, Room 10-A-38, Parklawn Building, 5600 Fishers Lane, 20857, Rockville, MD, USA aut NATIONALLICENCE 700 1- Strelow Loran Tobacco Research Laboratory, Department of Psychiatry, University of Minesota Medical School, Mayo Memorial Building, 420 Delaware Street SE, Box 392, 55455, Minneapolis, MN, USA aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 100/1(1990-03-01), 77-83 0033-3158 100:1<77 1990 100 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer