caa a22 4500 46573877X CHVBK 20180323111802.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02245797 doi (NATIONALLICENCE)springer-10.1007/BF02245797 Pirenperone does not attenuate morphine analgesia in spinal rats [Elektronische Daten] [Dennis Paul, John Pinel] The selective serotonin type-2 (S2) receptor blocker pirenperone (0.24 mg/kg, SC) attenuates morphine-produced tail-flick antinociception in intact rats, but not in rats with transected spinal cords. These results suggest that S2 receptor blockade does not affect intraspinal opioid antinociception. Together with evidence that there are virtually no S2 receptors in the dorsal spinal cord, supraspinal S2 receptors are implicated in the mediation of morphine-produced antinociception. Springer-Verlag, 1990 Pirenperone nationallicence Morphine nationallicence Spinal transection nationallicence Antinoception nationallicence S2 receptors nationallicence Paul Dennis Department of Psychology, University of British Columbia, V6T 1Y7, Vancouver, B.C., Canada aut Pinel John Department of Psychology, University of British Columbia, V6T 1Y7, Vancouver, B.C., Canada aut Psychopharmacology Springer-Verlag 100/1(1990-03-01), 98-101 0033-3158 100:1<98 1990 100 213 https://doi.org/10.1007/BF02245797 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02245797 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Paul Dennis Department of Psychology, University of British Columbia, V6T 1Y7, Vancouver, B.C., Canada aut NATIONALLICENCE 700 1- Pinel John Department of Psychology, University of British Columbia, V6T 1Y7, Vancouver, B.C., Canada aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 100/1(1990-03-01), 98-101 0033-3158 100:1<98 1990 100 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer