caa a22 4500 465738893 CHVBK 20180323111803.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02244597 doi (NATIONALLICENCE)springer-10.1007/BF02244597 Nootropic effects of ACE inhibitors in mice [Elektronische Daten] [C. Mondadori, P. Etienne] The angiotensin converting enzyme (ACE) inhibitors captopril and enalapril and the nootropic piracetam reduced the amnesiogenic effects of cerebral electroshock treatment in mice. These compounds also directly improved passive-avoidance learning if administered before the learning trial. When given immediately after the learning trial, captopril and piracetam were active, but not enalapril. Captopril, but neither enalapril nor piracetam, facilitated memory retrieval after a 2-month retention interval. Unlike those of piracetam, the memory-improving effects of captopril and enalapril are not established by aldosterone-receptor blockade, suggesting that the two types of drug act via different mechanisms of action. Springer-Verlag, 1990 ACE inhibitors nationallicence Captopril nationallicence Enalapril nationallicence Memory nationallicence Mice nationallicence Mondadori C. Ciba-Geigy, Pharmaceutical Research Department, CH-4002, Basel, Switzerland aut Etienne P. Department of Psychiatry 1033, McGill University, Pine Avenue West, H3A 1A1, Montreal, Quebec, Canada aut Psychopharmacology Springer-Verlag 100/3(1990-03-01), 301-307 0033-3158 100:3<301 1990 100 213 https://doi.org/10.1007/BF02244597 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02244597 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Mondadori C. Ciba-Geigy, Pharmaceutical Research Department, CH-4002, Basel, Switzerland aut NATIONALLICENCE 700 1- Etienne P. Department of Psychiatry 1033, McGill University, Pine Avenue West, H3A 1A1, Montreal, Quebec, Canada aut NATIONALLICENCE 773 0- Psychopharmacology Springer-Verlag 100/3(1990-03-01), 301-307 0033-3158 100:3<301 1990 100 213 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer