caa a22 4500 465742645 CHVBK 20180323111812.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02019533 doi (NATIONALLICENCE)springer-10.1007/BF02019533 Determination of thiamine (vitamin B1) in maternal blood during normal pregnancies and pregnancies with intrauterine growth retardation [Elektronische Daten] [T. Heinze, W. Weber] Summary: The concentration of thiamine (vitamin B1) was measured in blood cells and plasma from mothers with normal pregnancy and from mothers whose pregnancy was complicated by intrauterine growth retardation (IUGR). Thiamine concentrations were estimated by the thiochrome method using HPLC separation and fluorimetric detection according to Weber et al. (2). During normal pregnancies the thiamine values in blood cells fall in the 28th to the 39th week of gestation from 230 nmol/l to 170 nmol/l. In cases with severe IUGR there is only a slight decrease in the thiamine levels from 140 nmol/l in the 30th week of gestation to a level of 130 nmol/l in the 39th week of gestation. During this period the thiamine values in plasma remain constant. To compare the thiamine concentrations in normal pregnancies and in those with IUGR we separated the thiamine values in a group from 28/0 to 34/6 and one from 35/0 to 39/6 weeks of gestation. In both groups mothers with normal pregnancy had significantly higher thiamine levels in the blood cells than mothers whose pregnancy was complicated by IUGR (p=0.0001 and p=0.0005). However, the thiamine values in plasma were not significantly different in normal pregnancies and pregnancies with IUGR. The results indicate that maternal thiamine deficiency might be one cause of IUGR. Dr. Dietrich Steinkopff Verlag, 1990 t hiamine (vitamin B 1) nationallicence p regnancy nationallicence i ntrauterine growth retardation (IUGR) nationallicence T hiamin (Vitamin B1) nationallicence S chwangerschaft nationallicence i ntrauterine M angelentwicklung nationallicence Heinze T. Institute of Perinatal Medicine, Klinikum Rudolf Virchow, Free University of Berlin, Germany aut Weber W. Institute of Perinatal Medicine, Klinikum Rudolf Virchow, Free University of Berlin, Germany aut Zeitschrift für Ernährungswissenschaft Steinkopff-Verlag 29/1(1990-03-01), 39-46 0044-264X 29:1<39 1990 29 394 https://doi.org/10.1007/BF02019533 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02019533 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Heinze T. Institute of Perinatal Medicine, Klinikum Rudolf Virchow, Free University of Berlin, Germany aut NATIONALLICENCE 700 1- Weber W. Institute of Perinatal Medicine, Klinikum Rudolf Virchow, Free University of Berlin, Germany aut NATIONALLICENCE 773 0- Zeitschrift für Ernährungswissenschaft Steinkopff-Verlag 29/1(1990-03-01), 39-46 0044-264X 29:1<39 1990 29 394 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer