caa a22 4500 465742718 CHVBK 20180323111812.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF02021557 doi (NATIONALLICENCE)springer-10.1007/BF02021557 Parenteral β-carotene administration to cows: effect on plasma levels, lipoprotein distribution and secretion in the milk [Elektronische Daten] [F. Schweigert, W. Eisele] Summary: β-carotene has been considered to have a positive effect on fertility. Therefore the effect of a parenteral administration (intravenous or intramuscular) of β-carotene on plasma levels, its distribution among the lipoprotein fractions and its secretion in the milk was investigated in cows. A single parenteral administration of β-carotene resulted in a marked increase in total β-carotene in the blood. Low density lipoprotein (LDL)-bound β-carotene increased rapidly in the initial phase and then remained rather constant. The proportion bound to the high density fraction (HDL), however, increased continuously, reaching maximum levels parallel to the total plasma concentration. β-carotene administration had no effect on vitamin A levels in plasma, but caused an increase of β-carotene and vitamin A in milk. The results show that the parenteral administration of β-carotene is not only an effective way to increase its blood plasma level but also results in a binding of β-carotene to its physiological carrier — the lipoproteins. β-carotene is therefore supplied to peripheral target tissue by the same carriers as those when β-carotene is administered orally. The availability of β-carotene for peripheral tissues is further supported by the increase in β-carotene in milk, as well as by the increase in vitamin A in milk which points to a local conversion of β-carotene into vitamin A in the mammary gland. Dr. Dietrich Steinkopff Verlag, 1990 β-Carotin nationallicence Vitamin A nationallicence Lipoproteine nationallicence Milch nationallicence Rind nationallicence β-carotene nationallicence vitamin A nationallicence lipoproteins nationallicence milk nationallicence bovine nationallicence BC : β-carotene nationallicence VLDL : very-low density lipoproteins nationallicence LDL : low density lipoproteins nationallicence HDL : high density lipoproteins nationallicence i.m. : intramuscular nationallicence i.v. : intravenous nationallicence Schweigert F. Institute of Physiology, Physiological Chemistry and Nutrition Physiology, Veterinary Faculty, Ludwig-Maximilians-Universität München, FRG aut Eisele W. Institute of Physiology, Physiological Chemistry and Nutrition Physiology, Veterinary Faculty, Ludwig-Maximilians-Universität München, FRG aut Zeitschrift für Ernährungswissenschaft Steinkopff-Verlag 29/3(1990-09-01), 184-191 0044-264X 29:3<184 1990 29 394 https://doi.org/10.1007/BF02021557 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02021557 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Schweigert F. Institute of Physiology, Physiological Chemistry and Nutrition Physiology, Veterinary Faculty, Ludwig-Maximilians-Universität München, FRG aut NATIONALLICENCE 700 1- Eisele W. Institute of Physiology, Physiological Chemistry and Nutrition Physiology, Veterinary Faculty, Ludwig-Maximilians-Universität München, FRG aut NATIONALLICENCE 773 0- Zeitschrift für Ernährungswissenschaft Steinkopff-Verlag 29/3(1990-09-01), 184-191 0044-264X 29:3<184 1990 29 394 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer