caa a22 4500 465744257 CHVBK 20180323111816.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF02241015 doi (NATIONALLICENCE)springer-10.1007/BF02241015 Persistence of the carrier status in haemorrhagic septicaemia ( pasteurella multocida serotype 6:B infection) in Buffaloes [Elektronische Daten] [M. de Alwis, Thula Wijewardana, Anoma Gomis, A. Vipulasiri] Persistance De La Situation De Porteur Chez Des Buffles Atteints De Septicemie Hemorragique A Pasteurella Multocida , Serotype 6:B Summary: Fifty-seven young buffaloes were experimentally infected or naturally exposed to haemorrhagic septicaemia (HS). Of these animals 32 became immune carriers. They were observed in groups for periods up to 360 days to monitor the appearance of pasteurellae in the nasopharynx and antibody status. In most animals pasteurellae appeared in the nasopharynx for a short period initially and disappeared. The organism reappeared intermittently and the longest observed period of reappearance was 215 days after exposure. All animals showed rising antibody titres with a peak lasting for 150 to 180 days and declining thereafter. Pasteurellae persisted in the tonsils and were isolated from 20 out of 27 carriers after slaughter. The longest period when isolation was made after slaughter was 229 days. The organism lodged in the tonsils was unaffected by antibacterial therapy using drugs to which the organism displayedin vitro sensitivity. It is concluded that in HS, carrier animals exist in an active as well as a latent state, the former appearing for short intermittent periods between long latent periods, when pasteurellae continue to remain in the tonsils which constitute a long-term reservoir. Centre for Tropical Veterinary Medicine, 1990 de Alwis M. Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut Wijewardana Thula Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut Gomis Anoma Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut Vipulasiri A. Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut Tropical Animal Health and Production Kluwer Academic Publishers-Human Sciences Press 22/3(1990-09-01), 185-194 0049-4747 22:3<185 1990 22 11250 https://doi.org/10.1007/BF02241015 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02241015 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- de Alwis M. Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut NATIONALLICENCE 700 1- Wijewardana Thula Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut NATIONALLICENCE 700 1- Gomis Anoma Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut NATIONALLICENCE 700 1- Vipulasiri A. Veterinary Research Institute, Gannoruwa, Peradeniya, Sri Lanka aut NATIONALLICENCE 773 0- Tropical Animal Health and Production Kluwer Academic Publishers-Human Sciences Press 22/3(1990-09-01), 185-194 0049-4747 22:3<185 1990 22 11250 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer