caa a22 4500 465745032 CHVBK 20180323111818.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF01808133 doi (NATIONALLICENCE)springer-10.1007/BF01808133 Prebiotic synthesis of orotic acid parallel to the biosynthetic pathway [Elektronische Daten] [Y. Yamagata, K. Sasaki, O. Takaoka, S. Sano, K. Inomata, K. Kanemitsu, Y. Inoue, I. Matsumoto] By heating an aqueous solution of aspartic acid and urea, carbamylaspartic acid is first formed and then the molecule is cyclized to dihydroorotic acid (DHO) with loss of water. Irradiation of an aqueous solution of DHO with a tungsten lamp yields orotic acid by photo-dehydrogenation of the molecule. This pathway of orotic acid formation is quite similar to that of biosynthesis of the molecule. Kluwer Academic Publishers, 1990 Yamagata Y. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut Sasaki K. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut Takaoka O. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut Sano S. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut Inomata K. Department of Chemistry, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut Kanemitsu K. Division of Human Genetics, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku-gun, 920-02, Ishikawa, Japan aut Inoue Y. Division of Human Genetics, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku-gun, 920-02, Ishikawa, Japan aut Matsumoto I. Division of Human Genetics, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku-gun, 920-02, Ishikawa, Japan aut Origins of life and evolution of the biosphere Kluwer Academic Publishers 20/5(1990-09-01), 389-399 0169-6149 20:5<389 1990 20 11084 https://doi.org/10.1007/BF01808133 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01808133 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yamagata Y. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Sasaki K. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Takaoka O. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Sano S. Department of Physics, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Inomata K. Department of Chemistry, Faculty of Science, Kanazawa University, Marunouchi 1-1, 920, Kanazawa, Japan aut NATIONALLICENCE 700 1- Kanemitsu K. Division of Human Genetics, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku-gun, 920-02, Ishikawa, Japan aut NATIONALLICENCE 700 1- Inoue Y. Division of Human Genetics, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku-gun, 920-02, Ishikawa, Japan aut NATIONALLICENCE 700 1- Matsumoto I. Division of Human Genetics, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku-gun, 920-02, Ishikawa, Japan aut NATIONALLICENCE 773 0- Origins of life and evolution of the biosphere Kluwer Academic Publishers 20/5(1990-09-01), 389-399 0169-6149 20:5<389 1990 20 11084 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer