caa a22 4500 465745237 CHVBK 20180323111818.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02624717 doi (NATIONALLICENCE)springer-10.1007/BF02624717 Influence of cardiovascular diseases upon the results of the cardiovascular reflex tests in diabetic and nondiabetic subjects [Elektronische Daten] [Kornelia Krönert, Katrin Holder, Gudrun Kuschmierz, Birgit Mayer, Walter Renn, Dieter Luft, Manfred Eggstein] Summary: Cardiovascular reflex tests are used to assess cardiac autonomic neuropathy in diabetes mellitus. Cardiovascular diseases (CVD) are known to alter baroreflex mechanisms. Diabetic patients are at a high risk for cardiovascular complications. In order to prove whether cardiovascular diseases reduce the diagnostic value of the cardiovascular reflex tests in diabetic autonomic neuropathy unselected groups of 274 nondiabetic and 103 diabetic patients were studied: E/I, 30/15, and Valsalva ratios, sustained handgrip test and blood pressure response to standing. Both groups were subdivided into young (≤45 years) and older (>45 years) patients and into subjects with and without CVD. In young nondiabetic patients with CVD, E/I and Valsalva ratios were significantly lower than in those without CVD. In young diabetic patients with CVD, only E/I ratios were significantly reduced compared to those without CVD. The tests reflecting sympathetic nerve function did not differ between patients with and without CVD, neither in the nondiabetic nor in the diabetic subjects. In the older nondiabetic and diabetic patients, cardiovascular reflexes were generally impaired, but did not show any difference between subjects with and without CVD. In young diabetic patients suffering from CVD, the diagnostic value of cardiovascular reflex tests is reduced as far as cardiac autonomic neuropathy is concerned. In older patients, the tests are not suitable for the diagnosis of diabetic autonomic neuropathy. More specific methods are required. Casa Editrice «il Ponte», 1990 Cardiovascular diseases nationallicence Cardiovascular reflex tests nationallicence Diabetic autonomic neuropathy nationallicence Krönert Kornelia Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut Holder Katrin Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut Kuschmierz Gudrun Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut Mayer Birgit Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut Renn Walter Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut Luft Dieter Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut Eggstein Manfred Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut Acta diabetologia latina Springer-Verlag 27/1(1990-03-01), 1-10 0001-5563 27:1<1 1990 27 592 https://doi.org/10.1007/BF02624717 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02624717 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Krönert Kornelia Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut NATIONALLICENCE 700 1- Holder Katrin Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut NATIONALLICENCE 700 1- Kuschmierz Gudrun Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut NATIONALLICENCE 700 1- Mayer Birgit Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut NATIONALLICENCE 700 1- Renn Walter Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut NATIONALLICENCE 700 1- Luft Dieter Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut NATIONALLICENCE 700 1- Eggstein Manfred Abteilung Innere Medizin IV, Medizinische Universitätsklinik, Otfried-Müller-Strasse 10, D-7400, Tübingen, FRG aut NATIONALLICENCE 773 0- Acta diabetologia latina Springer-Verlag 27/1(1990-03-01), 1-10 0001-5563 27:1<1 1990 27 592 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer