caa a22 4500 465747000 CHVBK 20180323111823.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00322253 doi (NATIONALLICENCE)springer-10.1007/BF00322253 Vandeginste B. Catholic University of Nijmegen, NL-6525 ED, Nijmegen, The Netherlands aut Cheometrics in the daily laboratory practice [Elektronische Daten] [B. Vandeginste] Summary: Developments in computing technology have drastically changed the way analyses are performed in the analytical research and routine laboratory. More complex calculations are possible on data measured by microcomputer controlled instruments. Moreover affordable hardware and software became available for the development and implementation of knowledge based systems, which are an important tool to tackle problems which can not be solved in an algorithmic way. As the extraction of relevant analytical information from large and complex data structures became more accessible, instrument development was further pushed in the direction of higher complexity of operation and data. Chemometrics and, recently, knowledge engineering, have produced tools to support the analyst at various stages during the analysis; method development, calibration, optimisation, signal processing and method validation. Apparently these tools are becoming the building blocks of intelligent analytical workstations arranged in the socalled "intelligent laboratory”. By a system analysis of the activities in an analytical laboratory, the functionalities of the intelligent laboratory are discussed. Furthermore, the current status of the intelligent laboratory is evaluated in terms of available systems, systems expected to become available in the near future and "black spots” are identified for which no tools are yet available, requiring more chemometrics input. This overview comprises aspects of method development, the validation of analytical results and the processing of these results into information. Examples are chosen from the intelligent chromatography and intelligent spectroscopy laboratory. Springer-Verlag, 1990 Fresenius' Journal of Analytical Chemistry Springer-Verlag 337/7(1990-01-01), 786-793 0937-0633 337:7<786 1990 337 216 https://doi.org/10.1007/BF00322253 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00322253 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Vandeginste B. Catholic University of Nijmegen, NL-6525 ED, Nijmegen, The Netherlands aut NATIONALLICENCE 773 0- Fresenius' Journal of Analytical Chemistry Springer-Verlag 337/7(1990-01-01), 786-793 0937-0633 337:7<786 1990 337 216 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer