caa a22 4500 46574737X CHVBK 20180323111824.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00322221 doi (NATIONALLICENCE)springer-10.1007/BF00322221 Application of promethazine hydrochloride as a chromogenic reagent for the spectrophotometric determination of certain sulphonamide drugs [Elektronische Daten] [Mouayed Al-Abachi, E. Salih, M. Salem] Summary: The oxidative coupling reaction of promethazine · HCl with primary aromatic amines was applied to the determination of seven pharmaceutical sulphonamides. A mixture of an acidic solution (3.5% acetic acid) of the sulphonamide and the chromogenic reagent was treated with hypochloriteion. The wavelength of maximum absorption is 610 nm, the molar absorptivities range from 1.57×104 to 1.89×104 l mole−1 cm−1 and Sandell sensitivities range from 0.00972 to 0.0136 μg cm−2. A linear correlation was found between absorbance at λmax and concentration. The procedures developed for bulk sulpha drugs and some of their pharmaceutical preparations are rapid, accurate, precise and comparable to the Bratton-Marshall procedure. Springer-Verlag, 1990 Al-Abachi Mouayed Department of Chemistry, College of Education, University of Mosul, Mosul, IRAQ aut Salih E. Department of Chemistry, College of Education, University of Mosul, Mosul, IRAQ aut Salem M. Department of Chemistry, College of Education, University of Mosul, Mosul, IRAQ aut Fresenius' Journal of Analytical Chemistry Springer-Verlag 337/4(1990-01-01), 408-411 0937-0633 337:4<408 1990 337 216 https://doi.org/10.1007/BF00322221 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00322221 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Al-Abachi Mouayed Department of Chemistry, College of Education, University of Mosul, Mosul, IRAQ aut NATIONALLICENCE 700 1- Salih E. Department of Chemistry, College of Education, University of Mosul, Mosul, IRAQ aut NATIONALLICENCE 700 1- Salem M. Department of Chemistry, College of Education, University of Mosul, Mosul, IRAQ aut NATIONALLICENCE 773 0- Fresenius' Journal of Analytical Chemistry Springer-Verlag 337/4(1990-01-01), 408-411 0937-0633 337:4<408 1990 337 216 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer