caa a22 4500 465748767 CHVBK 20180323111827.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00322496 doi (NATIONALLICENCE)springer-10.1007/BF00322496 Quality criteria for residue analysis and reference materials. Relationship between legal procedures and materials [Elektronische Daten] [Rainer Stephany, Leendert van Ginkel] Summary: For qualitative results objective reliability checks are often not present at all or applicable. Interlaboratory ring testing of methods, as sometimes required, showed often not to be applicable simply because enough adequate laboratories are not available. For instance this situation applied to the large number of methods of unclear reliability status, to be used for residue monitoring of hormonal growth promotors (anabolic agents), which are completely banned within the European Communities since January 1988. This impasse was circumvented in 1987 with the formulation by an international group of analytical experts of a set of quality criteria for common analytical techniques like TLC, GC and HPLC (separation), UV, MS and IR spectrometry (detection) and immunoassays (separation and detection). These criteria, now published, are overviewed, as well as the availability of the control and reference materials belonging to them for actual analytical quality control and for validation of laboratories. Although developed for anabolic agents this new approach is applicable in practice for nearly all organic analytes and since very recently also for heavy metals. This approach has clear consequences for the mandatory quality of legislative residue analyses of food stuffs. As based on, amongst others, the combined experience of regulatory residue chemists within the EC, a collection of experimental selectivity indices is presented to rank the required specificity of regulatory residue methods (ranging from within laboratory orientation to international forensic purposes) in an objective way. Finally an estimate is summarized of the financial consequences of the applicable analytical techniques. Springer-Verlag, 1990 Stephany Rainer RIVM, P.O. Box 1, NL-3720 BA, Bilthoven, The Netherlands aut van Ginkel Leendert RIVM, P.O. Box 1, NL-3720 BA, Bilthoven, The Netherlands aut Fresenius' Journal of Analytical Chemistry Springer-Verlag 338/4(1990-01-01), 370-377 0937-0633 338:4<370 1990 338 216 https://doi.org/10.1007/BF00322496 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00322496 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Stephany Rainer RIVM, P.O. Box 1, NL-3720 BA, Bilthoven, The Netherlands aut NATIONALLICENCE 700 1- van Ginkel Leendert RIVM, P.O. Box 1, NL-3720 BA, Bilthoven, The Netherlands aut NATIONALLICENCE 773 0- Fresenius' Journal of Analytical Chemistry Springer-Verlag 338/4(1990-01-01), 370-377 0937-0633 338:4<370 1990 338 216 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer