caa a22 4500 465748988 CHVBK 20180323111828.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00322539 doi (NATIONALLICENCE)springer-10.1007/BF00322539 Determination of boron and lithium in diverse biological matrices using neutron activation-mass spectrometry (NA-MS) [Elektronische Daten] [G. Iyengar, W. Clarke, R. Downing] Summary: Essential features of the neutron activation-mass Spectrometry (NA-MS) technique are described. Applicability of this technique for the simultaneous determination of boron and lithium is demonstrated for a diverse group of biomaterials. NA-MS is a nondestructive analytical technique, and dynamic in nature since its coverage extends to a broad range of concentration levels. Contamination after the irradiation step, extraneous by natural lithium or boron is inconsequential, since only the activation products are the analyted assayed. Coupling the nuclear activation phenomenon which generates 4He and 3He (from 10B and 6Li, respectively), with the high precision potential of mass spectrometry forms the bases of this technique. Under ideal conditions the detection limit is extendable to pg g−1 concentration ranges and therefore, it is extremely well suited to investigate the natural concentration levels of boron and lithium in biomaterials. The potential of this method for the determination of lithium in biomedical trace element research is of special significance since determination of sub-ppb levels of lithium by other analytical techniques faces serious analytical difficulties mainly due to contamination control and in some cases to insufficiently low detection limits. Springer-Verlag, 1990 Iyengar G. NIST, 20899, Gaithersburg, MD, USA aut Clarke W. McMaster University, L9C 3N5, Hamilton, Ont., Canada aut Downing R. NIST, 20899, Gaithersburg, MD, USA aut Fresenius' Journal of Analytical Chemistry Springer-Verlag 338/4(1990-01-01), 562-566 0937-0633 338:4<562 1990 338 216 https://doi.org/10.1007/BF00322539 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00322539 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Iyengar G. NIST, 20899, Gaithersburg, MD, USA aut NATIONALLICENCE 700 1- Clarke W. McMaster University, L9C 3N5, Hamilton, Ont., Canada aut NATIONALLICENCE 700 1- Downing R. NIST, 20899, Gaithersburg, MD, USA aut NATIONALLICENCE 773 0- Fresenius' Journal of Analytical Chemistry Springer-Verlag 338/4(1990-01-01), 562-566 0937-0633 338:4<562 1990 338 216 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer