caa a22 4500 465749127 CHVBK 20180323111828.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00322529 doi (NATIONALLICENCE)springer-10.1007/BF00322529 Reference materials for domoic acid, a marine neurotoxin [Elektronische Daten] [W. Hardstaff, W. Jamieson, J. Milley, M. Quilliam, P. Sim] Summary: Domoic acid was recognized recently [1, 2] to be a marine neurotoxin associated with shellfish harvested or cultured for use as human food. Evidence about the occurrence of domoic acid and its importance to shellfish industries is reviewed. The preparation and certification of two reference materials for the determination of domoic acid, an instrument calibration solution (DACS-1, released by the Marine Analytical Chemistry Standards Program [MACSP] in May, 1989), and a tissue reference material (MUS-1, homogenized soft tissues of Mytilus edulis, released by the MACSP in August, 1989) are described. We believe these are the first certified standards or reference materials to be available for the determination of shellfish toxins, a problem of increasing importance to aquaculturists and the seafood industry, as well as to agencies concerned with the safety of food. The tissue homogenate preparation techniques we have developed and used may be of general interest for the preparation of other tissue reference materials for the determination of other organic compounds, since the sealed, fluid homogenate samples seem acceptably stable without being continuously frozen or refrigerated. Springer-Verlag, 1990 Hardstaff W. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut Jamieson W. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut Milley J. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut Quilliam M. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut Sim P. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut Fresenius' Journal of Analytical Chemistry Springer-Verlag 338/4(1990-01-01), 520-525 0937-0633 338:4<520 1990 338 216 https://doi.org/10.1007/BF00322529 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00322529 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hardstaff W. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut NATIONALLICENCE 700 1- Jamieson W. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut NATIONALLICENCE 700 1- Milley J. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut NATIONALLICENCE 700 1- Quilliam M. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut NATIONALLICENCE 700 1- Sim P. Marine Analytical Chemistry Standards Program, Institute for Marine Biosciences, National Research Council of Canada, 1411 Oxford Street, B3H 3Z1, Halifax, Nova Scotia, Canada aut NATIONALLICENCE 773 0- Fresenius' Journal of Analytical Chemistry Springer-Verlag 338/4(1990-01-01), 520-525 0937-0633 338:4<520 1990 338 216 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer