caa a22 4500 465752349 CHVBK 20180323111837.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF01576277 doi (NATIONALLICENCE)springer-10.1007/BF01576277 Prognosis in disseminated prostate cancer as related to tumor ploidy and differentiation [Elektronische Daten] [Ralph White, Arline Deitch, Henry Tesluk, Kathleen Lamborn, Frederick Meyers] Summary: Two flow cytometric studies of hormonally treated, widely disseminated (stage D2) prostate cancer are reported in which pretreatment DNA histograms were compared with prognosis. For 29 patients studied retrospectively, no significant difference in survival was found between those with DNA diploid tumors and those having aneuploid tumors. For 37 patients studied prospectively, the median time to disease progression was estimated to be 24 months for those DNA diploid tumors and 15 months for those having aneuploid tumors. The difference in estimated time to progression did not reach statistical significance (P=0.17). For 35 of these patients, who were followed for at least 12 months after hormonal ablation, 73% of those with diploid tumors and 81% of those having aneuploid tumors had experienced disease progression by 30 months after therapy. Springer-Verlag, 1990 White Ralph Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut Deitch Arline Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut Tesluk Henry Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut Lamborn Kathleen Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut Meyers Frederick Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut World Journal of Urology Springer-Verlag 8/1(1990-03-01), 47-50 0724-4983 8:1<47 1990 8 345 https://doi.org/10.1007/BF01576277 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01576277 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- White Ralph Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut NATIONALLICENCE 700 1- Deitch Arline Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut NATIONALLICENCE 700 1- Tesluk Henry Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut NATIONALLICENCE 700 1- Lamborn Kathleen Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut NATIONALLICENCE 700 1- Meyers Frederick Department of Urology, University of California, Davis, 4301 X Street, Suite 2220, 95817, Sacramento, CA, USA aut NATIONALLICENCE 773 0- World Journal of Urology Springer-Verlag 8/1(1990-03-01), 47-50 0724-4983 8:1<47 1990 8 345 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer