caa a22 4500 465752594 CHVBK 20180323111838.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF01576767 doi (NATIONALLICENCE)springer-10.1007/BF01576767 Nucleolar organiser regions as predictors of outcome in prostatic carcinoma [Elektronische Daten] [P. Gillen, P. Grace, P. Dervan, M. McDermott, J. Smith, J. Fitzpatrick] Summary: In a study of 45 patients with prostatic carcinoma and 10 with benign hyperplasia, nucleolar organiser regions (NORs) were counted to test the hypothesis that these loops of DNA, which transcribe to ribosomal RNA, have prognostic significance. The results showed significantly higher NOR scores in patients with cancer than in those with benign hyperplasia (p<0.05), with the highest scores being recorded in those destined to develop metastases at a later date. We conclude that this technique may have prognostic significance and warrants further prospective investigation. Springer-Verlag, 1990 Gillen P. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut Grace P. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut Dervan P. Department of Pathology, Mater Misericordiae Hospital University College, 47 Eccles Street, Dublin, Ireland aut McDermott M. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut Smith J. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut Fitzpatrick J. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut World Journal of Urology Springer-Verlag 8/3(1990-09-01), 175-178 0724-4983 8:3<175 1990 8 345 https://doi.org/10.1007/BF01576767 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01576767 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Gillen P. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut NATIONALLICENCE 700 1- Grace P. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut NATIONALLICENCE 700 1- Dervan P. Department of Pathology, Mater Misericordiae Hospital University College, 47 Eccles Street, Dublin, Ireland aut NATIONALLICENCE 700 1- McDermott M. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut NATIONALLICENCE 700 1- Smith J. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut NATIONALLICENCE 700 1- Fitzpatrick J. Department of Surgery/Urology, Mater Misericordiae Hospital, 47 Eccles Street, Dublin, Ireland aut NATIONALLICENCE 773 0- World Journal of Urology Springer-Verlag 8/3(1990-09-01), 175-178 0724-4983 8:3<175 1990 8 345 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer