caa a22 4500 46575273X CHVBK 20180323111838.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF01576352 doi (NATIONALLICENCE)springer-10.1007/BF01576352 The medical treatment of impotence: An update [Elektronische Daten] [Alvaro Morales, Jeremy Heaton] Summary: Improved understanding of penile physiology has enabled a better therapeutic approach to the treatment of impotence. The injection of vaso-active drugs into the corpora cavernosa is highly effective in a large proportion of patients, but it has major drawbacks. With the exception of hormonal abnormalities in which supplemental or suppressive medication results in a high proportion of cures, the search for effective oral or transcutaneous medication has not yet resulted in dramatic clinical success. Most research has been centered on adrenoceptor antagonists, which have exhibited only limited activity. Other compounds include vaso-dilators such as nitroglycerine, which have shown the ability to enhance tumescence, but their effectiveness remains to be proven. Dopamine receptor agonists are another group of agents of some efficacy that are now under study. The complexity of interactions among the various central and peripheral neurotransmitters suggests that effective therapy for impotence may require a combination of drugs. Renewed efforts in this direction, with proper clinical trials, are justified and hold significant promise. Springer-Verlag, 1990 Morales Alvaro Department of Urology and Human Sexuality Center, Queen's University, Kingston General Hospital, K7L 2V7, Kingston, Ontario, Canada aut Heaton Jeremy Department of Urology and Human Sexuality Center, Queen's University, Kingston General Hospital, K7L 2V7, Kingston, Ontario, Canada aut World Journal of Urology Springer-Verlag 8/2(1990-06-01), 80-83 0724-4983 8:2<80 1990 8 345 https://doi.org/10.1007/BF01576352 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01576352 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Morales Alvaro Department of Urology and Human Sexuality Center, Queen's University, Kingston General Hospital, K7L 2V7, Kingston, Ontario, Canada aut NATIONALLICENCE 700 1- Heaton Jeremy Department of Urology and Human Sexuality Center, Queen's University, Kingston General Hospital, K7L 2V7, Kingston, Ontario, Canada aut NATIONALLICENCE 773 0- World Journal of Urology Springer-Verlag 8/2(1990-06-01), 80-83 0724-4983 8:2<80 1990 8 345 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer