caa a22 4500 465752810 CHVBK 20180323111838.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF01576353 doi (NATIONALLICENCE)springer-10.1007/BF01576353 The use of prostaglandin E1 for diagnosis and treatment of erectile dysfunction [Elektronische Daten] [W. Stackl, R. Hasun, M. Marberger] Summary: Since 1982, many substances have been used for intracavernous injection to produce erections. Because the first-generation drugs (phenoxybenzamine, papaverine) were associated with severe side effects, including priapism and fibrosis of the penis, it was important that a safe and effective substance for intracavernous injection be found. In our series of 550 men with erectile dysfunction who received a test dose of 20 μg prostaglandin E1, 385 (70%) developed an erection lasting more than 30 min. Side effects were minimal: only one patient required treatment for priapism, and no fibrosis was found. A total of 275 patients entered an autoinjection protocol. All of these men were capable of engaging in intercourse and experienced no major side effects. In conclusion, prostaglandin E1 is effective, safe and preferable to all other drugs currently used for intracavernous injection. Springer-Verlag, 1990 Stackl W. Department of Urology, Rudolfstiftung, Juchgasse 25, A-1030, Vienna, Austria aut Hasun R. Department of Urology, Rudolfstiftung, Juchgasse 25, A-1030, Vienna, Austria aut Marberger M. Department of Urology, Rudolfstiftung, Juchgasse 25, A-1030, Vienna, Austria aut World Journal of Urology Springer-Verlag 8/2(1990-06-01), 84-86 0724-4983 8:2<84 1990 8 345 https://doi.org/10.1007/BF01576353 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01576353 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Stackl W. Department of Urology, Rudolfstiftung, Juchgasse 25, A-1030, Vienna, Austria aut NATIONALLICENCE 700 1- Hasun R. Department of Urology, Rudolfstiftung, Juchgasse 25, A-1030, Vienna, Austria aut NATIONALLICENCE 700 1- Marberger M. Department of Urology, Rudolfstiftung, Juchgasse 25, A-1030, Vienna, Austria aut NATIONALLICENCE 773 0- World Journal of Urology Springer-Verlag 8/2(1990-06-01), 84-86 0724-4983 8:2<84 1990 8 345 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer