caa a22 4500 465752993 CHVBK 20180323111839.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF01600303 doi (NATIONALLICENCE)springer-10.1007/BF01600303 The reproducibility of cytomorphometrical grading of bladder tumours [Elektronische Daten] [H. van der Poel, M. Boon, E. van der Meulen, A. Wijsman-Grootendorst] Summary: The reproducibility of cytomorphometrical nuclear area measurements on transitional cell carcinoma is studied. The inter-individual consistency is low (r=0.55,P=0.0005) when nuclei for measurement are chosen at random. When we use a systematic analysis based on cell situation and cytological features of malignancy to select the 50 nuclei for measurement per slide, the consistency between two technicians appears to be significantly higher (r=0.90,P=0.015). Not only interindividual consistency increases using the selection, but the correlation with histological tumour grade also improves significantly for both technicians. The results show that cytomorphometry is a method of grading bladder carcinoma when an accurate selection of nuclei to measure is used. Cytomorphometrical studies should contain a clear description of the way the nuclei for measurement are chosen. Springer-Verlag, 1990 Bladder tumour nationallicence Grade nationallicence Cytomorphometry nationallicence Reproducibility nationallicence van der Poel H. Leiden Cytology and Pathology Laboratory, P.O. Box 16084, 2301, GB Leiden, The Netherlands aut Boon M. Leiden Cytology and Pathology Laboratory, P.O. Box 16084, 2301, GB Leiden, The Netherlands aut van der Meulen E. Department of Mathematics, University of Groningen, Groningen, The Netherlands aut Wijsman-Grootendorst A. Leiden Cytology and Pathology Laboratory, P.O. Box 16084, 2301, GB Leiden, The Netherlands aut Virchows Archiv A Springer-Verlag 416/6(1990-11-01), 521-525 0174-7398 416:6<521 1990 416 428 https://doi.org/10.1007/BF01600303 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01600303 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- van der Poel H. Leiden Cytology and Pathology Laboratory, P.O. Box 16084, 2301, GB Leiden, The Netherlands aut NATIONALLICENCE 700 1- Boon M. Leiden Cytology and Pathology Laboratory, P.O. Box 16084, 2301, GB Leiden, The Netherlands aut NATIONALLICENCE 700 1- van der Meulen E. Department of Mathematics, University of Groningen, Groningen, The Netherlands aut NATIONALLICENCE 700 1- Wijsman-Grootendorst A. Leiden Cytology and Pathology Laboratory, P.O. Box 16084, 2301, GB Leiden, The Netherlands aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 416/6(1990-11-01), 521-525 0174-7398 416:6<521 1990 416 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer