caa a22 4500 465753019 CHVBK 20180323111839.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF01600305 doi (NATIONALLICENCE)springer-10.1007/BF01600305 Solid-cystic tumour of the pancreas [Elektronische Daten] An endocrine neoplasm? [A. von Herbay, B. Sieg, H. Otto] Summary: Immunohistochemical studies and DNA flow-cytometric investigations were performed in a case of solid-cystic tumour of the pancreas in a 35-year-old woman. All tumour cells were immunoreactive for the neuroendocrine cell markers chromogranin A and neuron-specificγ-enolase. Moreover, about 10% of tumour cells were immunoreactive for insulin, while hypoglycaemia was absent. Few tumour cells (less than 1%) were immunoreactive for somatostatin, and no cells were found to be immunoreactive for pancreatic polypeptide or glucagon. No immunoreactivity was present for duct cell marker carcino-embryonic antigen and only individual cells were reactive forα 1-antitrypsin. Nuclear DNA content of the tumour cells was diploid and the proliferative activity was low. In confirmation of some reports on neuroendocrine markers in solid-cystic tumour of the pancreas, our findings support the theory that the lesion is a hormonally inactive neuroendocrine pancreatic tumour. Springer-Verlag, 1990 Pancreatic tumour nationallicence Immunohistochemistry nationallicence Flow cytometry nationallicence von Herbay A. Pathologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 220/221, D-6900, Heidelberg 1, Federal Republic of Germany aut Sieg B. Pathologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 220/221, D-6900, Heidelberg 1, Federal Republic of Germany aut Otto H. Pathologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 220/221, D-6900, Heidelberg 1, Federal Republic of Germany aut Virchows Archiv A Springer-Verlag 416/6(1990-11-01), 535-538 0174-7398 416:6<535 1990 416 428 https://doi.org/10.1007/BF01600305 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01600305 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- von Herbay A. Pathologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 220/221, D-6900, Heidelberg 1, Federal Republic of Germany aut NATIONALLICENCE 700 1- Sieg B. Pathologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 220/221, D-6900, Heidelberg 1, Federal Republic of Germany aut NATIONALLICENCE 700 1- Otto H. Pathologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 220/221, D-6900, Heidelberg 1, Federal Republic of Germany aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 416/6(1990-11-01), 535-538 0174-7398 416:6<535 1990 416 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer