caa a22 4500 465753086 CHVBK 20180323111839.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF01678986 doi (NATIONALLICENCE)springer-10.1007/BF01678986 Pancreatoblastoma with marked elevation of serum alpha-fetoprotein [Elektronische Daten] An autopsy case report with immunocytochemical study [Toshio Morohoshi, Fumiaki Sagawa, Toshiyuki Mitsuya] Summary: The autopsy findings in a pancreatoblastoma in a 7-year-old Japanese girl is reported. The tumour was in the head and body of the pancreas, and was associated with diffuse carcinomatous peritonitis and hepatic and pulmonary metastases. There was marked elevation (more than 10000 ng/ml) of serum alpha-fetoprotein (AFP). Histopathologically the tumour was composed of solid epithelial elements with fibrous stroma, showing acinar arrangement, squamoid clusters and tubular structures. The epithelial elements contained numerous fine PAS positive granules in the cytoplasm. Immunocytochemical results suggested epithelial differentiation with positivity to alpha-1-antitrypsin (AAT), keratin, CA19-9, and AFP. No endocrine elements were recognized. Characteristic feature of this tumour are discussed and compared with prevoius reports. Springer-Verlag, 1990 Pancreatic neoplasm nationallicence Glandular epithelial neoplasm nationallicence Child nationallicence Alpha nationallicence fetoprotein nationallicence Immunohistochemistry nationallicence Morohoshi Toshio Ist Department of Pathology, Showa University School of Medicine, Hatanodai, Shinagawa-ku, Tokyo, Japan aut Sagawa Fumiaki Department of pathology, Fujigaoka Hospital, Showa University, Yokohama, Japan aut Mitsuya Toshiyuki Department of pathology, Fujigaoka Hospital, Showa University, Yokohama, Japan aut Virchows Archiv A Springer-Verlag 416/3(1990-05-01), 265-270 0174-7398 416:3<265 1990 416 428 https://doi.org/10.1007/BF01678986 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01678986 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Morohoshi Toshio Ist Department of Pathology, Showa University School of Medicine, Hatanodai, Shinagawa-ku, Tokyo, Japan aut NATIONALLICENCE 700 1- Sagawa Fumiaki Department of pathology, Fujigaoka Hospital, Showa University, Yokohama, Japan aut NATIONALLICENCE 700 1- Mitsuya Toshiyuki Department of pathology, Fujigaoka Hospital, Showa University, Yokohama, Japan aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 416/3(1990-05-01), 265-270 0174-7398 416:3<265 1990 416 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer