caa a22 4500 465753388 CHVBK 20180323111840.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF01605153 doi (NATIONALLICENCE)springer-10.1007/BF01605153 Primary lipid cardiomyopathy [Elektronische Daten] [Arthur Zimmermann, Peter Wyss, Franco Stocker] Summary: In this communication, we describe an isolated, apparently congenital cardiomyopathy (CMP) characterized by the accumulation of stainable lipid in mitochondria of cardiomyocytes. This lesion, which we term primary lipid cardiomyopathy, has not been reported so far. The structural alteration was associated with progressive heart failure, leading to death at the age of 3 years, and with massive hypertrophy of myocardium. Lipid storage in heart muscle cells resulted in an impressive yellow to orange color of the myocardium. We suggest that this type of primary CMP may represent a new member within the group of mitochondrial CMPs. Possible pathogenic mechanisms are discussed. Springer-Verlag, 1990 Cardiomyopathy nationallicence Lipid myopathy nationallicence Congenital heart disease nationallicence Zimmermann Arthur Institute of Pathology, University of Bern, Bern, Switzerland aut Wyss Peter Institute of Pathology, University of Bern, Bern, Switzerland aut Stocker Franco Pediatric University Clinic, Bern, Switzerland aut Virchows Archiv A Springer-Verlag 416/5(1990-09-01), 453-459 0174-7398 416:5<453 1990 416 428 https://doi.org/10.1007/BF01605153 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01605153 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zimmermann Arthur Institute of Pathology, University of Bern, Bern, Switzerland aut NATIONALLICENCE 700 1- Wyss Peter Institute of Pathology, University of Bern, Bern, Switzerland aut NATIONALLICENCE 700 1- Stocker Franco Pediatric University Clinic, Bern, Switzerland aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 416/5(1990-09-01), 453-459 0174-7398 416:5<453 1990 416 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer