caa a22 4500 465753434 CHVBK 20180323111840.0 cr unu---uuuuu 170327e19900901xx s 000 0 eng 10.1007/BF01605150 doi (NATIONALLICENCE)springer-10.1007/BF01605150 The spleen in osteomyelofibrosis [Elektronische Daten] A morphological and immunohistochemical study of 30 cases [Stephan Falk, Detlef Mix, Hans-Jochen Stutte] Summary: 30 spleens from patients with biopsy proven primary osteomyelofibrosis were studied by histological and immunohistochemical methods. The presence of trilinear haematopoiesis along the splenic circulatory pathway supports the theory that the spleen acquires haematopoietic precursor cells by filtration of the peripheral blood. In addition, impairment of intrasplenic circulation with subsequent red pulp congestion, pulp cord fibrosis and haemophagocytosis is of importance for the pathogenesis of both marked splenic haematopoiesis and complications due to hypersplenism. Springer-Verlag, 1990 Hematopoiesis nationallicence Immunohistochemistry nationallicence Osteomyelofibrosis nationallicence Spleen nationallicence Falk Stephan Department of Pathology, J.W. Goethe University, Theodor-Stern-Kai 7, D-6000, Frankfurt 70, West Germany aut Mix Detlef Department of Pathology, J.W. Goethe University, Theodor-Stern-Kai 7, D-6000, Frankfurt 70, West Germany aut Stutte Hans-Jochen Department of Pathology, J.W. Goethe University, Theodor-Stern-Kai 7, D-6000, Frankfurt 70, West Germany aut Virchows Archiv A Springer-Verlag 416/5(1990-09-01), 437-442 0174-7398 416:5<437 1990 416 428 https://doi.org/10.1007/BF01605150 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01605150 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Falk Stephan Department of Pathology, J.W. Goethe University, Theodor-Stern-Kai 7, D-6000, Frankfurt 70, West Germany aut NATIONALLICENCE 700 1- Mix Detlef Department of Pathology, J.W. Goethe University, Theodor-Stern-Kai 7, D-6000, Frankfurt 70, West Germany aut NATIONALLICENCE 700 1- Stutte Hans-Jochen Department of Pathology, J.W. Goethe University, Theodor-Stern-Kai 7, D-6000, Frankfurt 70, West Germany aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 416/5(1990-09-01), 437-442 0174-7398 416:5<437 1990 416 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer