caa a22 4500 465753493 CHVBK 20180323111840.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF01600112 doi (NATIONALLICENCE)springer-10.1007/BF01600112 Hepatoid adenocarcinoma: A distinctive histological subtype of alpha-fetoprotein-producing lung carcinoma [Elektronische Daten] [Hiroshi Ishikura, Makoto Kanda, Motohiko Ito, Kenji Nosaka, Kazuya Mizuno] Summary: Seven cases of alpha-fetoprotein (AFP)-producing lung carcinoma were studied histologically to determine whether they fell into any previously described category. The patients were all males from 40 to 73 years of age and their serum AFP levels ranged from 1039 to 320000 ng/ml. Five cases of hepatoid adenocarcinoma, one case of endodermal sinus tumour, and one case of papillary adenocarcinoma were found. The possible origins of the tumours and their differential diagnosis are discussed. Hepatoid adenocarcinoma is a major histological category among AFP-producing lung carcinoma; other types are less frequent. The occurrence of hepatoid adenocarcinoma in both the stomach and the lung suggests that this neoplasm may also be seen in other organs of endodermal origin. It may be a major histological subtype of AFP-producing endodermal neoplasms of non-germ cell origin. Springer-Verlag, 1990 Alpha-fetoprotein nationallicence Lung carcinoma nationallicence Hepatoid adenocarcinoma nationallicence Endodermal sinus tumour nationallicence Ishikura Hiroshi The Department of Pathology, Hokkaido University School of Medicine, Sapporo aut Kanda Makoto The Department of Pathology, Asahikawa City General Hospital, Asahikawa aut Ito Motohiko The Department of Surgery, Utano National Hospital, Kyoto aut Nosaka Kenji The Department of Pathology, Kanto Central Hospital, Tokyo aut Mizuno Kazuya The Department of Microbiology, Hokkaido University School of Medicine, Sapporo, Japan aut Virchows Archiv A Springer-Verlag 417/1(1990-01-01), 73-80 0174-7398 417:1<73 1990 417 428 https://doi.org/10.1007/BF01600112 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01600112 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Ishikura Hiroshi The Department of Pathology, Hokkaido University School of Medicine, Sapporo aut NATIONALLICENCE 700 1- Kanda Makoto The Department of Pathology, Asahikawa City General Hospital, Asahikawa aut NATIONALLICENCE 700 1- Ito Motohiko The Department of Surgery, Utano National Hospital, Kyoto aut NATIONALLICENCE 700 1- Nosaka Kenji The Department of Pathology, Kanto Central Hospital, Tokyo aut NATIONALLICENCE 700 1- Mizuno Kazuya The Department of Microbiology, Hokkaido University School of Medicine, Sapporo, Japan aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 417/1(1990-01-01), 73-80 0174-7398 417:1<73 1990 417 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer