caa a22 4500 465753582 CHVBK 20180323111840.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF01600103 doi (NATIONALLICENCE)springer-10.1007/BF01600103 Nucleolar organiser regions in hyperplastic and neoplastic prostatic tissue [Elektronische Daten] [A. Hansen, B. Østergård] Summary: Silver-stained nucleolar organiser regions (AgNORs) were studied in 10 hyperplastic, 5 intra-epithelial neoplastic and 30 malignant prostatic lesions. Total AgNOR counts and types were compared with histological features. The total AgNOR count per nucleus was significantly higher (p<0.05) in prostatic intra-epithelial neoplasia (PIN) and adenocarcinoma compared with prostatic hyperplasia. In addition, satellite Ag-NORs predominated in hyperplasia, while medium-sized and large nucleoli with granular AgNORs were only observed in PIN and adenocarcinoma. The results indicate that, despite statistically significant differences, Ag-NOR counts are of no use for diagnosis of any single case in the groups studied, because of considerable overlap. AgNOR typing, however, may contribute to the differential diagnosis between benign and malignant lesions. We propose a new AgNOR typing system. Springer-Verlag, 1990 Prostate tumours nationallicence Hyperplasia nationallicence Adenocarcinoma nationallicence Nucleolar organiser regions nationallicence DNA nationallicence Hansen A. Department of Pathology, Holstebro Hospital, DK-7500, Holstebro, Denmark aut Østergård B. Department of Pathology, Holstebro Hospital, DK-7500, Holstebro, Denmark aut Virchows Archiv A Springer-Verlag 417/1(1990-01-01), 9-13 0174-7398 417:1<9 1990 417 428 https://doi.org/10.1007/BF01600103 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01600103 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hansen A. Department of Pathology, Holstebro Hospital, DK-7500, Holstebro, Denmark aut NATIONALLICENCE 700 1- Østergård B. Department of Pathology, Holstebro Hospital, DK-7500, Holstebro, Denmark aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 417/1(1990-01-01), 9-13 0174-7398 417:1<9 1990 417 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer