caa a22 4500 46575371X CHVBK 20180323111841.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF01625729 doi (NATIONALLICENCE)springer-10.1007/BF01625729 Immunohistochemical expression of glutathione S-transferase placental type (GST-π), a detoxifying enzyme, in normal arachnoid villi and meningiomas [Elektronische Daten] [A. Hara, H. Yamada, N. Sakai, H. Hirayama, T. Tanaka, H. Mori] Summary: Human normal dura mater containing arachnoid villi were examined for their expression of glutathione S-transferase placental type (GST-π), a detoxifying enzyme, using an immunohistochemical method. All of the arachnoid villi and arachnoid cells in five normal cases were found to have expression of GST-π, although no positive reaction for the enzyme was present in other tissues of the dura mater. The results show a possible role for arachnoid tissues in protecting human brain from hazardous xenobiotics in the cerebrospinal fluid. Twenty-six meningiomas were also examined for expression of the enzyme. Tissues of meningotheliomatous meningiomas were always positive for expression of the enzyme. Transitional meningiomas also showed the expression in their meningotheliomatous components. No staining reaction of GST-π was recognized in fibroblastic meningiomas except for two cases with a tendency to meningotheliomatous differentiation. The findings suggest a functional similarity between the arachnoid tissues and meningotheliomatous components of meningiomas. Springer-Verlag, 1990 Arachnoid villi nationallicence Meningioma nationallicence Glutathione S-transferase placental type nationallicence Cerebrospinal fluid nationallicence Hara A. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut Yamada H. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut Sakai N. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut Hirayama H. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut Tanaka T. Department of Pathology, Gifu University School of Mediine, Gifu, Japan aut Mori H. Department of Pathology, Gifu University School of Mediine, Gifu, Japan aut Virchows Archiv A Springer-Verlag 417/6(1990-11-01), 493-496 0174-7398 417:6<493 1990 417 428 https://doi.org/10.1007/BF01625729 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01625729 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hara A. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut NATIONALLICENCE 700 1- Yamada H. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut NATIONALLICENCE 700 1- Sakai N. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut NATIONALLICENCE 700 1- Hirayama H. Department of Neurosurgery, Gifu University School of Mediine, 40 Tsukasamachi, 500, Gifu city, Japan aut NATIONALLICENCE 700 1- Tanaka T. Department of Pathology, Gifu University School of Mediine, Gifu, Japan aut NATIONALLICENCE 700 1- Mori H. Department of Pathology, Gifu University School of Mediine, Gifu, Japan aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 417/6(1990-11-01), 493-496 0174-7398 417:6<493 1990 417 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer