caa a22 4500 465753728 CHVBK 20180323111841.0 cr unu---uuuuu 170327e19901101xx s 000 0 eng 10.1007/BF01625733 doi (NATIONALLICENCE)springer-10.1007/BF01625733 Role of amyloid in dialysis-related arthropathies [Elektronische Daten] A morphological analysis of 23 cases [Manel Solé, José Muñoz-Gómez, Josep Campistol] Summary: The role of beta2-microglobulin-related amyloidosis in the articular syndromes associated with longterm haemodialysis was analysed in a series of 23 haemodialysed patients from whom 43 amyloid-containing osteoarticular specimens were obtained. Patients with clinical arthropathy had more intense and deep synovial involvement by amyloid than asymptomatic ones. Amyloid proved to be an agent for bone destruction, causing bone cysts and cortical erosions. Amyloid deposition in cartilage was found constantly, leading to fissures and irregularities in the articular surface. From our observations, amyloid seems to be the main pathogenetic factor involved in articular swelling, destructive arthropathies and pathological fractures occurring in haemodialysed patients, although other disturbances related to haemodialysis could play a role. Springer-Verlag, 1990 Amyloid arthropathy nationallicence Beta2-microglobulin nationallicence Haemodialysis nationallicence Solé Manel Services of Pathology, Hospital Clínic i Provincial, University of Barcelona, Barcelona, Spain aut Muñoz-Gómez José Services of Rheumatology, Hospital Clínic i Provincial, University of Barcelona, Barcelona, Spain aut Campistol Josep Services of Renal Transplant Unit, Hospital Clínic i Provincial, University of Barcelona, Barcelona, Spain aut Virchows Archiv A Springer-Verlag 417/6(1990-11-01), 523-528 0174-7398 417:6<523 1990 417 428 https://doi.org/10.1007/BF01625733 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01625733 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Solé Manel Services of Pathology, Hospital Clínic i Provincial, University of Barcelona, Barcelona, Spain aut NATIONALLICENCE 700 1- Muñoz-Gómez José Services of Rheumatology, Hospital Clínic i Provincial, University of Barcelona, Barcelona, Spain aut NATIONALLICENCE 700 1- Campistol Josep Services of Renal Transplant Unit, Hospital Clínic i Provincial, University of Barcelona, Barcelona, Spain aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 417/6(1990-11-01), 523-528 0174-7398 417:6<523 1990 417 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer