caa a22 4500 465753760 CHVBK 20180323111841.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF01600139 doi (NATIONALLICENCE)springer-10.1007/BF01600139 Boquist L. Institute of Pathology, University of Umeå, S-901 87, Umeå, Sweden aut Nucleolar organizer regions in normal, hyperplastic and neoplastic parathyroid glands [Elektronische Daten] [L. Boquist] Summary: Using a one-stage silver staining technique, nucleolar organizer regions (AgNORs) were studied in paraffin sections of parathyroid glands (and in two lymph node metastases) from patients operated upon because of hyperparathyroidism or thyroid disease. The parathyroids were microscopically differentiated into normal, hyperplastic, adenomatous and carcinomatous glands. AgNORs were observed as distinct black dots of varying size and somewhat varying configuration in the nuclei of all glands. The mean number of AgNORs in the hyperplastic and adenomatous glands was not significantly different from that in the normal glands, whereas the carcinomatous glands exhibited significantly increased mean AgNOR number. No evidence was obtained for a role of AgNOR counting in the differentiation between normal and hyperplastic or adenomatous parathyroids, but the results suggest a potential role of enumeration of AgNORs in the discrimination between benign and malignant parathyroid neoplasms. Springer-Verlag, 1990 Adenoma nationallicence Carcinoma nationallicence Hyperplasia nationallicence Nucleolar organizer regions nationallicence Parathyroids nationallicence Virchows Archiv A Springer-Verlag 417/3(1990-05-01), 237-241 0174-7398 417:3<237 1990 417 428 https://doi.org/10.1007/BF01600139 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01600139 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Boquist L. Institute of Pathology, University of Umeå, S-901 87, Umeå, Sweden aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 417/3(1990-05-01), 237-241 0174-7398 417:3<237 1990 417 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer