caa a22 4500 465753892 CHVBK 20180323111841.0 cr unu---uuuuu 170327e19900701xx s 000 0 eng 10.1007/BF01605789 doi (NATIONALLICENCE)springer-10.1007/BF01605789 A case of alveolar rhabdomyosarcoma with a chromosomal translocation, t(2; 13) (q37; q14) [Elektronische Daten] [Takayuki Nojima, Syuiti Abe, Hideo Yamaguchi, Takeo Matsuno, Kazuaki Inoue] Summary: We report on an alveolar rhabdomyosarcoma occurring in a 17-year-old girl. Histologically, the tumour exhibited a proliferation of small, round cells and formed alveolar structures. Immunohistochemical studies of the tumour cells showed desmin and creatine kinase MM positivity. In electron-microscopic studies, the tumour cells showed an abundance of glycogen granules, and myofilaments were recognized in the cytoplasm. Chromosome analysis revealed a translocation, t(2; 13)(q37; q14), which is thought to be common in this subtype of rhabdomyosarcoma. Conventional ultrastructural and immunohistochemical investigations and chromosome analysis thus appear to be a highly promising combination of methods for improved pathological diagnosis of alveolar rhabdomyosarcoma. Springer-Verlag, 1990 Rhabdomyosarcoma nationallicence alveolar type nationallicence Karyo-typing nationallicence Pathological diagnosis nationallicence Nojima Takayuki Department of Pathology, Hokkaido University School of Medicine, Kita 14 Nishi 5, Kita-ku, 060, Sapporo, Japan aut Abe Syuiti Chromosome Research Unit, Faculty of Science, Hokkaido University, Sapporo, Japan aut Yamaguchi Hideo Department of Orthopaedic Surgery, Hokkaido University School of Medicine, Sapporo, Japan aut Matsuno Takeo Department of Orthopaedic Surgery, Hokkaido University School of Medicine, Sapporo, Japan aut Inoue Kazuaki Department of Pathology, Hokkaido University School of Medicine, Kita 14 Nishi 5, Kita-ku, 060, Sapporo, Japan aut Virchows Archiv A Springer-Verlag 417/4(1990-07-01), 357-359 0174-7398 417:4<357 1990 417 428 https://doi.org/10.1007/BF01605789 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF01605789 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Nojima Takayuki Department of Pathology, Hokkaido University School of Medicine, Kita 14 Nishi 5, Kita-ku, 060, Sapporo, Japan aut NATIONALLICENCE 700 1- Abe Syuiti Chromosome Research Unit, Faculty of Science, Hokkaido University, Sapporo, Japan aut NATIONALLICENCE 700 1- Yamaguchi Hideo Department of Orthopaedic Surgery, Hokkaido University School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Matsuno Takeo Department of Orthopaedic Surgery, Hokkaido University School of Medicine, Sapporo, Japan aut NATIONALLICENCE 700 1- Inoue Kazuaki Department of Pathology, Hokkaido University School of Medicine, Kita 14 Nishi 5, Kita-ku, 060, Sapporo, Japan aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 417/4(1990-07-01), 357-359 0174-7398 417:4<357 1990 417 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer