caa a22 4500 46575418X CHVBK 20180323111842.0 cr unu---uuuuu 170327e19900601xx s 000 0 eng 10.1007/BF02190537 doi (NATIONALLICENCE)springer-10.1007/BF02190537 Granular cell tumour of the appendix in a patient irradiated for a rectal carcinoma [Elektronische Daten] [Miriam Pipeleers-Marichal, Anita Goossens, Boudewijn De Waele, Günter Klöppel] Summary: We report on a 47-year-old man with a granular cell tumour of the appendix, discovered incidentally during surgery for a rectal adenocarcinoma that had been irradiated preoperatively. A detailed immunocytochemical analysis revealed positivity for S-100 and neuron-specific enolase (NSE). Electron microscopically, the cytoplasm of the tumour cells contained numerous pleomorphic lysosomes. In the appendix tissue adjacent to the tumour a neuroma and the histological features of radiation injury were present. Our findings suggest that this granular cell tumour may have originated from a pre-existing appendix neuroma which underwent granular degeneration, possibly as a result of radiation. Springer-Verlag, 1990 Granular cell tumour nationallicence Appendiceal neuroma nationallicence Appendix nationallicence Radiation injury nationallicence Pipeleers-Marichal Miriam Department of Pathology, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut Goossens Anita Department of Pathology, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut De Waele Boudewijn Department of Surgery, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut Klöppel Günter Department of Pathology, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut Virchows Archiv A Springer-Verlag 417/2(1990-06-01), 177-180 0174-7398 417:2<177 1990 417 428 https://doi.org/10.1007/BF02190537 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02190537 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Pipeleers-Marichal Miriam Department of Pathology, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut NATIONALLICENCE 700 1- Goossens Anita Department of Pathology, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut NATIONALLICENCE 700 1- De Waele Boudewijn Department of Surgery, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut NATIONALLICENCE 700 1- Klöppel Günter Department of Pathology, Academic Hospital, Free University of Brussels, Laarbeeklaan 101, B-1090, Brussels, Belgium aut NATIONALLICENCE 773 0- Virchows Archiv A Springer-Verlag 417/2(1990-06-01), 177-180 0174-7398 417:2<177 1990 417 428 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer