caa a22 4500 465757480 CHVBK 20180323111851.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF00327020 doi (NATIONALLICENCE)springer-10.1007/BF00327020 A mutated swi4 gene causes duplications in the mating-type region of Schizosaccharomyces pombe [Elektronische Daten] [Oliver Fleck, Lutz Heim, Herbert Gutz] Summary: Efficient mating-type (MT) switching in homothallic strains of Schizosaccharomyces pombe is significantly reduced if they have a mutation in any of the eleven known swi genes. The swi4 mutation causes heterothallic as well as homothallic segregants, both of which have duplications in the MT region. In contrast to homothallic strains, h + swi4 strains yield only a few duplications. The duplications originate in the process of MT switching, presumably by mistakes in the resolution of DNA intermediates. They always consist of one cassette and one of the intervening sequences, L and K respectively. Strains with up to seven cassettes in the MT region were found. The possible modes of their origins are discussed. Springer-Verlag, 1990 Mating-type switching nationallicence swi genes nationallicence Duplications nationallicence Schizosaccharomyces pombe nationallicence Fleck Oliver Institut für Genetik, Technische Universität Braunschweig, Konstantin-Uhde-Strasse 5, W-3300, Braunschweig, Germany aut Heim Lutz Institut für Genetik, Technische Universität Braunschweig, Konstantin-Uhde-Strasse 5, W-3300, Braunschweig, Germany aut Gutz Herbert Institut für Genetik, Technische Universität Braunschweig, Konstantin-Uhde-Strasse 5, W-3300, Braunschweig, Germany aut Current Genetics Springer-Verlag 18/6(1990-12-01), 501-509 0172-8083 18:6<501 1990 18 294 https://doi.org/10.1007/BF00327020 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00327020 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Fleck Oliver Institut für Genetik, Technische Universität Braunschweig, Konstantin-Uhde-Strasse 5, W-3300, Braunschweig, Germany aut NATIONALLICENCE 700 1- Heim Lutz Institut für Genetik, Technische Universität Braunschweig, Konstantin-Uhde-Strasse 5, W-3300, Braunschweig, Germany aut NATIONALLICENCE 700 1- Gutz Herbert Institut für Genetik, Technische Universität Braunschweig, Konstantin-Uhde-Strasse 5, W-3300, Braunschweig, Germany aut NATIONALLICENCE 773 0- Current Genetics Springer-Verlag 18/6(1990-12-01), 501-509 0172-8083 18:6<501 1990 18 294 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer