caa a22 4500 46575869X CHVBK 20180323111854.0 cr unu---uuuuu 170327e19900401xx s 000 0 eng 10.1007/BF00314872 doi (NATIONALLICENCE)springer-10.1007/BF00314872 The effect of DNA replication on mutation of the Saccharomyces cerevisiae CDC8 gene [Elektronische Daten] [D. Zaborowska, J. Zuk] Summary: Incubation in YPD medium under permissive conditions when DNA replication is going on, strongly stimulates the induction of cdc+ colonies of UV-irradiated cells of yeast strains HB23 (cdc8-1/cdc8-3), HB26 (cdc8-3/cdc8-3) and HB7 (cdc8-1/cdc8-1). Inhibition of DNA replication by hydroxyurea, araCMP, cycloheximide or caffeine or else by incubation in phosphate buffer pH 7.0, abolishes this stimulation. Thus the replication of DNA is strongly correlated with the high induction of cdc+ colonies by UV irradiation. It is postulated that these UV-induced cdc+ colonies arise as the result infidelity in DNA replication. Springer-Verlag, 1990 Yeast nationallicence DNA replication nationallicence Effect on mutation nationallicence Zaborowska D. Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Rakowiecka 36, 02-532, Warsaw, Poland aut Zuk J. Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Rakowiecka 36, 02-532, Warsaw, Poland aut Current Genetics Springer-Verlag 17/4(1990-04-01), 275-280 0172-8083 17:4<275 1990 17 294 https://doi.org/10.1007/BF00314872 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00314872 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Zaborowska D. Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Rakowiecka 36, 02-532, Warsaw, Poland aut NATIONALLICENCE 700 1- Zuk J. Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Rakowiecka 36, 02-532, Warsaw, Poland aut NATIONALLICENCE 773 0- Current Genetics Springer-Verlag 17/4(1990-04-01), 275-280 0172-8083 17:4<275 1990 17 294 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer