caa a22 4500 465761852 CHVBK 20180323111901.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF02987101 doi (NATIONALLICENCE)springer-10.1007/BF02987101 Prognostic significance of general immune competence in acute leukemia [Elektronische Daten] [Li Bai-Ling, Hu Jie, Ye Jia, Wan Xiao-Feng, Shen Yi-Gao, Li Bing-Bing, Chen Yu-Chun, Lin Xin-Shun, Chen Yuan-Qing] The prognostic significance of lymphocyte transformation rate, E-RFC%, 29°C E-RFC%, serum IgG, IgA, IgM and C3 levels were studied in 286 patients with acute leukemia. In acute lymphoblastic leukemia (ALL), the pretreatment immunological parameters were not related to whether the patients could achieve complete remission (CR), but the patients with E-RFC% greater than 30% before treatment or E-RFC% restored to normal after treatment had a significantly longer survival time. In acute nonlymphocytic leukemia (ANLL), pretreatment LTR and E-RFC% were significantly higher in patients who could achieve CR subsequently, the patients with higher pretreatment levels of LTR, E-RFC% or 29°C E-RFC% survived significantly longer than patients with lower levels of these parameters, and the patients whose LTR could return to normal after treatment had a significantly higher CR rate and longer survival times. Except that the pretreatment IgM level was related to the survival of ANLL patients, serum levels of immunoglobulins and C3 had no prognostic value for both ALL and ANLL. In both ALL and ANLL, the immunological parameters changed significantly when relapse occurred. Humana Press Inc., 1990 Acute leukemia nationallicence Immune competence nationallicence Prognosis nationallicence Bai-Ling Li Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut Jie Hu Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut Jia Ye Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut Xiao-Feng Wan Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut Yi-Gao Shen Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut Bing-Bing Li Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut Yu-Chun Chen Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut Xin-Shun Lin Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut Yuan-Qing Chen Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut Medical Oncology and Tumor Pharmacotherapy Humana Press 7/4(1990-12-01), 233-239 0736-0118 7:4<233 1990 7 12032 https://doi.org/10.1007/BF02987101 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02987101 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Bai-Ling Li Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Jie Hu Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Jia Ye Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Xiao-Feng Wan Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Yi-Gao Shen Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Bing-Bing Li Department of Immunology, Fujian Provincial Institute of Medical Sciences, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Yu-Chun Chen Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Xin-Shun Lin Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut NATIONALLICENCE 700 1- Yuan-Qing Chen Department of Immunology, Fujian Provincial Institute of Traditional Chinese Medicine, Fuzhou, Fujian, People's Republic of China aut NATIONALLICENCE 773 0- Medical Oncology and Tumor Pharmacotherapy Humana Press 7/4(1990-12-01), 233-239 0736-0118 7:4<233 1990 7 12032 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer