caa a22 4500 465761909 CHVBK 20180323111901.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF02987108 doi (NATIONALLICENCE)springer-10.1007/BF02987108 ZAniboni A. III Divisione di Medicina, Servizio di Oncologia, Spedali Civili, 25100, Brescia, Italy aut Suramin: The discovery of an old anticancer drug [Elektronische Daten] [A. ZAniboni] Suramin, an antitrypanosomal agent used since the early 1920s for the treatment of onchocerciasis and African sleeping sickness is now under active investigation as an antineoplastic drug characterized by an unusual and interesting mechanism of action and by a peculiar pattern of toxicity. Its capacity to interfere with the autocrine loop which promotes the growth of many human tumors as well as the suggested ability to modify the tumoral environment (chiefly by inhibiting the angiogenesis) holds out great promises for a major step forward in cancer therapy. Humana Press Inc., 1990 Suramin nationallicence Growth factors nationallicence Medical Oncology and Tumor Pharmacotherapy Humana Press 7/4(1990-12-01), 287-290 0736-0118 7:4<287 1990 7 12032 https://doi.org/10.1007/BF02987108 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02987108 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- ZAniboni A. III Divisione di Medicina, Servizio di Oncologia, Spedali Civili, 25100, Brescia, Italy aut NATIONALLICENCE 773 0- Medical Oncology and Tumor Pharmacotherapy Humana Press 7/4(1990-12-01), 287-290 0736-0118 7:4<287 1990 7 12032 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer