caa a22 4500 465764088 CHVBK 20180323111908.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF00916369 doi (NATIONALLICENCE)springer-10.1007/BF00916369 Wound tissue respiratory burst and local microbial inflammation [Elektronische Daten] [Sandro Belotsky, Eugenij Guzu, Vladimir Karlov, Eugenia Dikovskaya, Olga Filjukova, Tatiana Snastina] Local and systemic chemiluminescent (CL) response was measured in 32 patients with wound infection and in 27 patients with crush syndrome complicated by severe wound infection. The level of wound CL depends upon the local microbial concentration and the dynamics of wound healing. CL response of neutrophils in circulation was higher in higher local CL response, but extremely high wound microbial concentration (> 108 CFU/g) suppressed both local and systemic responses. No metabolic reserve was observed in wound tissue. Wound healing was characterized by changes in the mode of local CL response: from a prevalence of luminol-dependent (neutrophilic) CL to a prevalence of lucigenin-independent (macrophagal) CL. Plenum Publishing Corporation, 1990 Belotsky Sandro A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut Guzu Eugenij A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut Karlov Vladimir A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut Dikovskaya Eugenia A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut Filjukova Olga A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut Snastina Tatiana A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut Inflammation Kluwer Academic Publishers-Plenum Publishers 14/6(1990-12-01), 663-668 0360-3997 14:6<663 1990 14 10753 https://doi.org/10.1007/BF00916369 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00916369 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Belotsky Sandro A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut NATIONALLICENCE 700 1- Guzu Eugenij A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut NATIONALLICENCE 700 1- Karlov Vladimir A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut NATIONALLICENCE 700 1- Dikovskaya Eugenia A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut NATIONALLICENCE 700 1- Filjukova Olga A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut NATIONALLICENCE 700 1- Snastina Tatiana A. V. Vishnevsky Institute of Surgery, Moscow, USSR aut NATIONALLICENCE 773 0- Inflammation Kluwer Academic Publishers-Plenum Publishers 14/6(1990-12-01), 663-668 0360-3997 14:6<663 1990 14 10753 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer