caa a22 4500 465764339 CHVBK 20180323111909.0 cr unu---uuuuu 170327e19901001xx s 000 0 eng 10.1007/BF00914280 doi (NATIONALLICENCE)springer-10.1007/BF00914280 Human phagocytic cells as oxygen metabolite scavengers [Elektronische Daten] [Elaine Berger, Connie Beehler, Ruth Harada, John Repine] Human neutrophils or monocytes decreased hydrogen peroxide (H2O2) concentrationsin vitro. Neutrophils or monocytes decreased H2O2 concentrations as well as human erythrocytes. Treatment with aminotriazole or azide decreased both phagocyte and erythrocyte catalase activity and the ability of each cell to decrease H2O2 concentrationsin vitro. Prestimulation of phagocytic cells with phorbol myristate acetate (PMA) or opsonized zymosan decreased neither their catalase activity nor their ability to decrease H2O2 concentrations. The results suggest that unstimulated or stimulated phagocytic cells can scavenge H2O2 and may potentially decrease H2O2-mediated tissue injury. The H2O2 scavenging potential of phagocytic cells is due at least partially to their catalase activity. Plenum Publishing Corporation, 1990 Berger Elaine Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut Beehler Connie Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut Harada Ruth Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut Repine John Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut Inflammation Kluwer Academic Publishers-Plenum Publishers 14/5(1990-10-01), 513-619 0360-3997 14:5<513 1990 14 10753 https://doi.org/10.1007/BF00914280 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00914280 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Berger Elaine Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut NATIONALLICENCE 700 1- Beehler Connie Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut NATIONALLICENCE 700 1- Harada Ruth Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut NATIONALLICENCE 700 1- Repine John Webb-Waring Lung Institute Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Colorado aut NATIONALLICENCE 773 0- Inflammation Kluwer Academic Publishers-Plenum Publishers 14/5(1990-10-01), 513-619 0360-3997 14:5<513 1990 14 10753 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer