caa a22 4500 465765289 CHVBK 20180323111912.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF00117785 doi (NATIONALLICENCE)springer-10.1007/BF00117785 Morphogenesis as a parallel of invasion: the epithelial-mesenchymal boundary and basal lamina in foetal rat colon [Elektronische Daten] [Carla Chrusch, Felix Bertalanffy, Ian Carr] : In order to determine whether neoplastic invasion, as it occurs in colonic carcinoma, represents a recapitulation of embryonic events, the development of the crypts and basal lamina of the rat colon was examined in foetuses between 16 and 21 days gestation by light and transmission electron microscopy, autoradiography and morphometric techniques. The thickness of the basal lamina increased from days 16 to 18 of gestation. On days 19 and 20 the basal lamina was found to be significantly thicker in the intercryptal areas than at the base of the crypt. This difference disappeared at 21 days gestation. It was also demonstrated that cell migration and renewal occur in the same manner in the foetal colon as in the adult colon. These features do not resemble closely those seen in neoplastic invasion. Taylor & Francis Ltd, 1990 Chrusch Carla Departments of Pathology and Anatomy, University of Manitoba, Manitoba, Canada aut Bertalanffy Felix Departments of Pathology and Anatomy, University of Manitoba, Manitoba, Canada aut Carr Ian Departments of Pathology and Anatomy, University of Manitoba, Manitoba, Canada aut Clinical & Experimental Metastasis Kluwer Academic Publishers 8/2(1990-03-01), 121-127 0262-0898 8:2<121 1990 8 10585 https://doi.org/10.1007/BF00117785 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00117785 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Chrusch Carla Departments of Pathology and Anatomy, University of Manitoba, Manitoba, Canada aut NATIONALLICENCE 700 1- Bertalanffy Felix Departments of Pathology and Anatomy, University of Manitoba, Manitoba, Canada aut NATIONALLICENCE 700 1- Carr Ian Departments of Pathology and Anatomy, University of Manitoba, Manitoba, Canada aut NATIONALLICENCE 773 0- Clinical & Experimental Metastasis Kluwer Academic Publishers 8/2(1990-03-01), 121-127 0262-0898 8:2<121 1990 8 10585 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer