caa a22 4500 465765882 CHVBK 20180323111913.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF02535903 doi (NATIONALLICENCE)springer-10.1007/BF02535903 Influence of dietary fatty acid composition on cholesterol synthesis and esterification in hamsters [Elektronische Daten] [Peter Jones, Julie Ridgen, Alexander Benson] To investigate the effects of dietary fat quality on synthesis and esterification of cholesterol, Syrian hamsters were fed diets containing corn, olive, coconut or menhaden oils (10% w/w) with added cholesterol (0.1% w/w). After 3 weeks, animals were sacrificed 90 min following IP injection of3H2O. Synthesis of free cholesterol and movement of free cholesterol into ester pools were measured from3H-uptade rate in liver and duodenum. Plasma total cholesterol and triglycerides levels were highest in coconut oil-fed animals, whereas hepatic total cholesterol and ester levels were elevated in olive oil-fed animals, as compared with all other groups. No diet-related differences were seen in duodenal cholesterol or total fatty acid content. In duodenum, uptake of3H per g tissue into cholesterol was greater compared with liver; however, within each tissue,3H-uptake into cholesterol was similar across groups. Notably,3H-uptake into cholesterol ester in liver was highest in menhaden oil-fed animals. These data suggest that menhaden fish oil consumption results in enhanced movement of newly synthesized cholesterol into ester as compared with other fat types. American Oil Chemists' Society, 1990 Jones Peter Division of Human Nutrition, School of Family and Nutritional Services, University of British Columbia, 2205 East Mall, V6T 1W5, Vancouver, British Columbia, Canada aut Ridgen Julie Division of Human Nutrition, School of Family and Nutritional Services, University of British Columbia, 2205 East Mall, V6T 1W5, Vancouver, British Columbia, Canada aut Benson Alexander Division of Human Nutrition, School of Family and Nutritional Services, University of British Columbia, 2205 East Mall, V6T 1W5, Vancouver, British Columbia, Canada aut Lipids Springer-Verlag 25/12(1990-12-01), 815-820 0024-4201 25:12<815 1990 25 11745 https://doi.org/10.1007/BF02535903 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02535903 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Jones Peter Division of Human Nutrition, School of Family and Nutritional Services, University of British Columbia, 2205 East Mall, V6T 1W5, Vancouver, British Columbia, Canada aut NATIONALLICENCE 700 1- Ridgen Julie Division of Human Nutrition, School of Family and Nutritional Services, University of British Columbia, 2205 East Mall, V6T 1W5, Vancouver, British Columbia, Canada aut NATIONALLICENCE 700 1- Benson Alexander Division of Human Nutrition, School of Family and Nutritional Services, University of British Columbia, 2205 East Mall, V6T 1W5, Vancouver, British Columbia, Canada aut NATIONALLICENCE 773 0- Lipids Springer-Verlag 25/12(1990-12-01), 815-820 0024-4201 25:12<815 1990 25 11745 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer