caa a22 4500 465765963 CHVBK 20180323111913.0 cr unu---uuuuu 170327e19901201xx s 000 0 eng 10.1007/BF02535911 doi (NATIONALLICENCE)springer-10.1007/BF02535911 The effect of bleomycin on the uptake and incorporation of [14C] choline into phospholipids in hamster lung tissue slices [Elektronische Daten] [Mannfred Hollinger, Shri Giri] Intratracheal administration of the anticancer drug bleomycin to hamsters produced an increase in the uptake and incorporation of [14C] choline into phospholipids of lung slicesin vitro. The stimulatory effect is opposite to the results obtained previously using [14C] acetate and would appear to occur distal to cytidine diphosphocholine. Although alternate explanations are possible, the results are consistent with morphological evidence, published by others, indicating an increase in lung phospholipid following bleomycin treatment, and illustrate the significance of precursor selection when evaluating the effects of xenobiotics on phospholipid synthesis. American Oil Chemists' Society, 1990 Hollinger Mannfred Departments of Pharmacology, School of Medicine and Veterinary Pharmacology and Toxicology, School of Veterinary Medicine, University of California, 95616, Davis, California aut Giri Shri Departments of Pharmacology, School of Medicine and Veterinary Pharmacology and Toxicology, School of Veterinary Medicine, University of California, 95616, Davis, California aut Lipids Springer-Verlag 25/12(1990-12-01), 863-866 0024-4201 25:12<863 1990 25 11745 https://doi.org/10.1007/BF02535911 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02535911 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Hollinger Mannfred Departments of Pharmacology, School of Medicine and Veterinary Pharmacology and Toxicology, School of Veterinary Medicine, University of California, 95616, Davis, California aut NATIONALLICENCE 700 1- Giri Shri Departments of Pharmacology, School of Medicine and Veterinary Pharmacology and Toxicology, School of Veterinary Medicine, University of California, 95616, Davis, California aut NATIONALLICENCE 773 0- Lipids Springer-Verlag 25/12(1990-12-01), 863-866 0024-4201 25:12<863 1990 25 11745 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer