caa a22 4500 465766110 CHVBK 20180323111914.0 cr unu---uuuuu 170327e19900301xx s 000 0 eng 10.1007/BF02544331 doi (NATIONALLICENCE)springer-10.1007/BF02544331 Carotenoids of human colostrum [Elektronische Daten] [Stuart Patton, Louise Canfield, Gail Huston, Ann Ferris, Robert Jensen] Colostrum, the initial postpartum secretion of the breast, ordinarily has a distinct yellow color due to carotenoids of its fat globules. This pigmentation progressively diminishes as milk production increases during the first week of lactation. Identity of these cartenoids was investigated by means of thin-layer chromatography, high performance liquid chromatography and spectral analysis. α- and β-carotene, lycopene and β-cryptoxanthin were revealed as major chromogens. A component corresponding to lutein and/or zeaxanthin was also detected by both chromatographic techniques. Extracts of 23 saponified colostrum samples from 10 donors revealed considerable variation in total carotenoid concentration (0.34-7.57 μg/ml of colostrum). Multiparous mothers had greater mean colostrum carotenoid concentrations than did the primiparae, 2.18±1.94 vs 1.14±1.32 μg/ml, respectively. Seven of the eight primiparous donors' samples had little or no yellow color. These findings imply a difference in carotenoid transport by breasts that have lactated as compared to those that have not. The interrelation of carotenoids, lactation and breast cancer is discussed. American Oil Chemists' Society (AOCS), 1985 Patton Stuart Department of Neurosciences, M-034J, University of California San Diego, 92093, La Jolla, CA aut Canfield Louise Department of Biochemistry, University of Arizona, 85724, Tucson, AZ aut Huston Gail Cancer Center, University of California San Diego, 92093, La Joila, CA aut Ferris Ann Department of Nutritional Sciences, University of Connecticut, 06268, Storrs, CT aut Jensen Robert Department of Nutritional Sciences, University of Connecticut, 06268, Storrs, CT aut Lipids Springer-Verlag 25/3(1990-03-01), 159-165 0024-4201 25:3<159 1990 25 11745 https://doi.org/10.1007/BF02544331 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02544331 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Patton Stuart Department of Neurosciences, M-034J, University of California San Diego, 92093, La Jolla, CA aut NATIONALLICENCE 700 1- Canfield Louise Department of Biochemistry, University of Arizona, 85724, Tucson, AZ aut NATIONALLICENCE 700 1- Huston Gail Cancer Center, University of California San Diego, 92093, La Joila, CA aut NATIONALLICENCE 700 1- Ferris Ann Department of Nutritional Sciences, University of Connecticut, 06268, Storrs, CT aut NATIONALLICENCE 700 1- Jensen Robert Department of Nutritional Sciences, University of Connecticut, 06268, Storrs, CT aut NATIONALLICENCE 773 0- Lipids Springer-Verlag 25/3(1990-03-01), 159-165 0024-4201 25:3<159 1990 25 11745 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer