caa a22 4500 465766536 CHVBK 20180323111915.0 cr unu---uuuuu 170327e19900501xx s 000 0 eng 10.1007/BF02544386 doi (NATIONALLICENCE)springer-10.1007/BF02544386 Effect of dietary α-linolenate/linoleate balance on crescent type-anti-glomerular basement membrane nephritis in rats [Elektronische Daten] [Shiro Watanabe, Erika Suzuki, Ryoji Kojima, Yoshio Suzuki, Harumi Okuyama] Rats were fed diets with three different ratios of α-linolenate (18∶3 n−3) and linoleate (18∶2 n−6), and then crescentic-type anti-glomerular basement membrane (GBM) nephritis was induced. The urinary protein levels and the plasma urea nitrogen levels were significantly higher, and histological abnormalities of glomeruli were seen more frequently in the high-α-linolenate group than in the high-linoleate group. The differences in dietary α-linolenate/linoleate balances were reflected in the proportions of arachidonate and eicosapentaenoate in glomerular phospholipids. Our results indicate that dietary enrichment with α-linolenate causes unfavorable effects in this anti-GBM nephritis model. American Oil Chemists' Society, 1990 Watanabe Shiro Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Mizuhoku, 467, Nagoya, Japan aut Suzuki Erika Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Mizuhoku, 467, Nagoya, Japan aut Kojima Ryoji Department of Pharmacology, Faculty of Pharmacy, Meijo University, Tenpakutu, 468, Nagoya, Japan aut Suzuki Yoshio Department of Pharmacology, Faculty of Pharmacy, Meijo University, Tenpakutu, 468, Nagoya, Japan aut Okuyama Harumi Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Mizuhoku, 467, Nagoya, Japan aut Lipids Springer-Verlag 25/5(1990-05-01), 267-272 0024-4201 25:5<267 1990 25 11745 https://doi.org/10.1007/BF02544386 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF02544386 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Watanabe Shiro Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Mizuhoku, 467, Nagoya, Japan aut NATIONALLICENCE 700 1- Suzuki Erika Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Mizuhoku, 467, Nagoya, Japan aut NATIONALLICENCE 700 1- Kojima Ryoji Department of Pharmacology, Faculty of Pharmacy, Meijo University, Tenpakutu, 468, Nagoya, Japan aut NATIONALLICENCE 700 1- Suzuki Yoshio Department of Pharmacology, Faculty of Pharmacy, Meijo University, Tenpakutu, 468, Nagoya, Japan aut NATIONALLICENCE 700 1- Okuyama Harumi Department of Biological Chemistry, Faculty of Pharmaceutical Sciences, Nagoya City University, Mizuhoku, 467, Nagoya, Japan aut NATIONALLICENCE 773 0- Lipids Springer-Verlag 25/5(1990-05-01), 267-272 0024-4201 25:5<267 1990 25 11745 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer