caa a22 4500 465767214 CHVBK 20180323111917.0 cr unu---uuuuu 170327e19900101xx s 000 0 eng 10.1007/BF00308720 doi (NATIONALLICENCE)springer-10.1007/BF00308720 Ho K. Department of Pathology, Henry Ford Hospital, 2799 West Grand Boulevard, 48202, Detroit, MI, USA aut Intercellular septate-like junction of neoplastic cells in myxopapillary ependymoma of the filum terminale [Elektronische Daten] [K. Ho] Summary: Septate junction, a common intercellular feature of invertebrate epithelium, is absent in most vertebrate tissues. In an ultrastructural study of three cases of myxopapillary ependymoma of the filum terminale, structures similar to septate junction were observed in two cases. They were circumferential bands around the finger-like processes of neoplastic cells in which slightly widened 30-40-nm intercellular spaces (as compared to 15-20 nm in nonjunctional region) were transversed at regular intervals by parallel septa resulting in characteristic ladder-like appearance. The electron-dense septa, 30-40 nm in cross-length and 20-30 nm in width, were arranged in a periodicity of 40-50 nm. The septa connected to the outer leaflets of the apposing cytoplasmic membranes which appear undisrupted. Most junctions were short; the longest one contained 15 septa in a length of 1.4 μm. Hemiseptate-like junctions with septa of the same measurements were noted between the processes and the investing basement membrane. Junetional complexes such as zonula adherens and gap junction were present in the vicinity. They may represent a specific intercellular feature of myxopapillary ependymoma, and function as cellular adhesions and a mechanical support of the neoplastic cells. Springer-Verlag, 1990 Filum terminale nationallicence Myxopapillary ependymoma nationallicence Septate junction nationallicence Septate-like junction nationallicence Intercellular junction nationallicence Acta Neuropathologica Springer-Verlag 79/4(1990-01-01), 432-437 0001-6322 79:4<432 1990 79 401 https://doi.org/10.1007/BF00308720 text/html Onlinezugriff via DOI 1 research-article jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00308720 text/html Onlinezugriff via DOI NATIONALLICENCE 100 1- Ho K. Department of Pathology, Henry Ford Hospital, 2799 West Grand Boulevard, 48202, Detroit, MI, USA aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 79/4(1990-01-01), 432-437 0001-6322 79:4<432 1990 79 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer