caa a22 4500 465767400 CHVBK 20180323111918.0 cr unu---uuuuu 170327e19900201xx s 000 0 eng 10.1007/BF00296119 doi (NATIONALLICENCE)springer-10.1007/BF00296119 Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain [Elektronische Daten] [H. Yamaguchi, C. Haga, S. Hirai, Y. Nakazato, K. Kosaka] Summary: We have developed a new methenamine silver (MS) stain for detecting diffuse plaques distinctively on paraffin-embedded tissue sections of Alzheimer-type dementia, Down'n syndrome, and mentally normal aged brains. This rapid and easy method selectively labels amyloid-related component of senile plaques, but not of kuru plaques found in Gerstmann-Sträussler syndrome. Our MS stain shows almost the same staining pattern as that of the β protein immunostaining with formic acid pretreatment. Therefore, new MS stain is appropriate to routine or screening studies for senile plaques including diffuse plaques. Springer-Verlag, 1990 Senile plaques nationallicence Methenamine silver stain nationallicence Alzheimer-type dementia nationallicence Down's syndrome nationallicence Amyloid β protein nationallicence Yamaguchi H. College of Medical Care and Technology, Gunma University, 3-39-15 Showa-machi, 371, Maebashi, Gunma, Japan aut Haga C. Psychiatric Research Institute of Tokyo, Tokyo, Japan aut Hirai S. Department of Neurology, Gunma University School of Medicine, 3-39-15 Showa-machi, 371, Maebashi, Gunma, Japan aut Nakazato Y. 1st Department of Pathology, Gunma University School of Medicine, 3-39-15 Showa-machi, Gunma 371, Maebashi, Japan aut Kosaka K. Psychiatric Research Institute of Tokyo, Tokyo, Japan aut Acta Neuropathologica Springer-Verlag 79/5(1990-02-01), 569-572 0001-6322 79:5<569 1990 79 401 https://doi.org/10.1007/BF00296119 text/html Onlinezugriff via DOI 1 brief-communication jats NATIONALLICENCE 856 40 https://doi.org/10.1007/BF00296119 text/html Onlinezugriff via DOI NATIONALLICENCE 700 1- Yamaguchi H. College of Medical Care and Technology, Gunma University, 3-39-15 Showa-machi, 371, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Haga C. Psychiatric Research Institute of Tokyo, Tokyo, Japan aut NATIONALLICENCE 700 1- Hirai S. Department of Neurology, Gunma University School of Medicine, 3-39-15 Showa-machi, 371, Maebashi, Gunma, Japan aut NATIONALLICENCE 700 1- Nakazato Y. 1st Department of Pathology, Gunma University School of Medicine, 3-39-15 Showa-machi, Gunma 371, Maebashi, Japan aut NATIONALLICENCE 700 1- Kosaka K. Psychiatric Research Institute of Tokyo, Tokyo, Japan aut NATIONALLICENCE 773 0- Acta Neuropathologica Springer-Verlag 79/5(1990-02-01), 569-572 0001-6322 79:5<569 1990 79 401 Metadata rights reserved Springer special CC-BY-NC licence nationallicence BK010053 XK010053 XK010000 NATIONALLICENCE NATIONALLICENCE NL-springer